Structural dimensions and number of floors are some of the factors affecting the building behaviour under the earthquake effects. In this study, the structural footprint and the number of floors were selected as a variable. For this purpose, a steel structure model with fixed dimensions and properties of load-bearing system elements was selected. The structural footprint was selected as the first variable and then five different structure models were created. The structural footprint was changed by setting each axial clearance in both directions. Each axial clearance was increased by 0.5m in each structure model. Three different number of floors as to be 5, 6 and 7 floors were selected as the second variable. Eigenvalue and pushover analyses were performed for each model and each number of floors. As a result of the analyses, the target displacement values for period, frequency, cumulative participation mass ratio, base shear force, settlement, stiffness and degree of damage were acquired separately. As the structural footprint and number of the floors increase, while the period, settlement and the target displacement values increased, on the contrary, there was a decrease in participation mass ratio, base shear forces and stiffness values. In the study, cost comparisons of building construction were also made considering the change in the total structural area and the number of floors. The criterion of safety and economy was ignored due to increase both in the number of floors and the footprint. This study emphasizes the importance of avoiding the unnecessary structural dimensions via optimum design principles. As structural footprint area and number of floors increase, period values increase, stiffness and seismic capacity values decrease. As the number of floors and footprint area increases, the total building area increases, so the approximate building cost has also increased.