Alternative splicing generates multiple transcripts of the inhibitor of apoptosis protein 1 in Aedes and Culex spp. mosquitoes

Beck, Eric T.; Blair, Carol D.; Black, William C.; Beaty, Barry J.; Blitvich, Bradley J.

doi:10.1016/j.ibmb.2007.07.015

Cited by 12 publications

(2 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Apoptosis, or programmed cell death, is an evolutionarily conserved process that regulates the normal development and homeostasis of multicellular organisms by removing unwanted, damaged, mutated, or infected cells [1]. The apoptotic cell death program results from the activation of caspases, a family of highly specific cysteine proteases essential for the death of the cell.…”

Section: Introductionmentioning

confidence: 99%

Notice of Retraction: Cloning of IAP Gene in Culex quinquefasciatus and Its Molecular Evolution Analysis

Zhang

et al. 2011

2011 5th International Conference on Bioinformatics and Biomedical Engineering

View full text Add to dashboard Cite

Inhibitor of apoptosis proteins (IAPs) constitute a family of proteins that contain one to three baculovirus IAP repeats(BIR). This IAP family ensure cell viability through binding to caspases with the BIR domain and regulating their activity in a ubiquitin-dependent manner. While IAPs are regulated by their antagonists. To investigate the regulation pathway of IAP, we have cloned and sequenced the Cqiap gene of Culex quinquefasciatus from China by RT -PCR. It's 1230bp in length. The putative protein of Cqiap contains two BIR domains and one RING finger domain. Cqiap is highly identity with iap of the published Culex quinquefasciatus (GENE ID: 6032833, 99.6%). Multiple sequence alignment and phylogenetic tree analysis show that animal IAPs were classified into two major groups. As to the species we list in this paper，one group is from invertebrate IAPs with two BIR domains, the other group contains invertebrate and vertebrate IAPs with three BIR domains. The reported IAP of Culex quinquefasciatus from China falls into the group of IAPs with 2 BIR domains.

show abstract

Section: Introductionmentioning

confidence: 99%

Notice of Retraction: Cloning of IAP Gene in Culex quinquefasciatus and Its Molecular Evolution Analysis

Zhang

et al. 2011

2011 5th International Conference on Bioinformatics and Biomedical Engineering

View full text Add to dashboard Cite

show abstract

“…Ae. triseriatus specific primers (AtrTOR-F and AtrTOR-R) were chosen from the sequence, and a primer walking technique was used to sequence the remainder of the gene.The 3ʹ and 5ʹ ends were sequenced using a rapid amplification of cDNA ends (RACE) PCR protocol(Beck et al 2007). The full-length transcript sequence was later confirmed and completed using Illumina mRNA-seq, and Bowtie) was used to map 104-nt short reads against sequences generated by traditional Sanger sequencing.Illumina mRNA-seq was used to sequence Aedes triseriatus ribosomal S6K (AtrS6K).…”

mentioning

confidence: 99%