Alternative Treatment Method for Novel Coronavirus Disease 2019: Coupled Plasma Filtration Adsorption

Çiftçi, Bahadır; Erdoğan, Cem; Kizilaslan, Deniz; Ekinci, Mine; Ölmüşçelik, Oktay; Atalay, Yunus Oktay

doi:10.5152/eurasianjmed.2021.20151

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Therapeutic Plasma Exchange (Tpe)1

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2022

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“…Although CPFA is a promising method there are not enough data in treating Covid-19 patients. Ciftci et al, in a case report used CPFA method in two patients with Covid-19 and improvement was observed in the clinical status and cytokine levels [33] . Similarly, in a retrospective study of 20 patients CPFA was demonstrated to be a well- tolerated and safe method with beneficial effects on oxygenation and sofa score through removal of pro-inflammatory mediators [34] .…”

Section: Therapeutic Plasma Exchange (Tpe)mentioning

confidence: 99%

Apheresis and COVID-19 in intensive care unit (ICU)

Xanthi¹,

Vasiliki²,

Aloizos³

2022

Transfusion and Apheresis Science

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Section: Therapeutic Plasma Exchange (Tpe)mentioning

confidence: 99%

Apheresis and COVID-19 in intensive care unit (ICU)

Xanthi¹,

Vasiliki²,

Aloizos³

2022

Transfusion and Apheresis Science

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Acute Kidney Injury and Blood Purification Techniques in Severe COVID-19 Patients

Napoli

Provenzano

et al. 2022

JCM

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Although most patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) experience respiratory manifestations, multi-organ dysfunction is frequent. Almost 20% of hospitalized patients with SARS-CoV-2 infection develop acute kidney injury (AKI). The pathophysiology of AKI is a result of both the direct and indirect effects of SARS-CoV-2 infection, including systemic inflammatory responses, the activation of the renin-angiotensin-aldosterone system (RAAS), and endothelial and coagulative dysfunction. Underlying SARS-CoV-2 infection-associated AKI, an immunological hyper-response with an unbalanced innate and adaptative response defined as a “cytokine storm” has emerged. Numerous agents have been tested in an effort to mitigate the cytokine storm, and a range of extracorporeal cytokine removal techniques have been proposed as potential therapeutic options. In the present review, we summarize the main pathogenetic mechanisms underlying COVID-19-related AKI in order to provide an appropriate individual therapeutic strategy to improve clinical outcomes and limit the progression of early disease.

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Alternative Treatment Method for Novel Coronavirus Disease 2019: Coupled Plasma Filtration Adsorption

Cited by 2 publications

References 5 publications

Apheresis and COVID-19 in intensive care unit (ICU)

Apheresis and COVID-19 in intensive care unit (ICU)

Acute Kidney Injury and Blood Purification Techniques in Severe COVID-19 Patients

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