2003
DOI: 10.1186/1471-2288-3-21
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Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio

Abstract: BackgroundCross-sectional studies with binary outcomes analyzed by logistic regression are frequent in the epidemiological literature. However, the odds ratio can importantly overestimate the prevalence ratio, the measure of choice in these studies. Also, controlling for confounding is not equivalent for the two measures. In this paper we explore alternatives for modeling data of such studies with techniques that directly estimate the prevalence ratio.MethodsWe compared Cox regression with constant time at ris… Show more

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Cited by 3,290 publications
(2,720 citation statements)
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“…We then compared the health status of PAH members to that of the general population sample by fitting robust Poisson regression models 31 to compute age-adjusted prevalence ratios (PR a ) of poor health status and their 95 % confidence intervals (95 % CI); we estimated PR a s overall and stratified by each explanatory variable. We obtained prevalence differences (PD) by subtracting the estimated age-standardized prevalence (Tables 2 and 3).…”
Section: Resultsmentioning
confidence: 99%
“…We then compared the health status of PAH members to that of the general population sample by fitting robust Poisson regression models 31 to compute age-adjusted prevalence ratios (PR a ) of poor health status and their 95 % confidence intervals (95 % CI); we estimated PR a s overall and stratified by each explanatory variable. We obtained prevalence differences (PD) by subtracting the estimated age-standardized prevalence (Tables 2 and 3).…”
Section: Resultsmentioning
confidence: 99%
“…Second, prevalence and 95% confidence intervals (95% CI) of the variables of interest were calculated. Given the cross‐sectional nature of the study, as well as potential high prevalence of the outcome of interest (Barros and Hirakata, 2003), the association between depression and glycemic control was evaluated using Poisson regression models with robust standard errors (Coutinho et al ., 2008), reporting prevalence ratios (PR) and 95% CI adjusted for potential confounders. Different models were fitted utilizing a hierarchical approach (Victora et al ., 1997), conducted to better understand the potential influence of covariates in the association of interest.…”
Section: Methodsmentioning
confidence: 99%
“…When the estimates are on or near the boundaries of the valid parameter space, the estimation algorithm will not converge. The convergence problem is most likely to happen when the model contains a continuous or polychotomous covariate, or the response prevalence is high [13,14]. The simulation studies by Carter et al [11] show that the estimates have poor properties when the success probability approaches 1.…”
Section: The Estimation Methodsmentioning
confidence: 99%
“…As the actual response follows a binomial distribution, the variance of the coefficient β̂k tends to be overestimated [13]. Barros and Hirakata [13] and Zou [10] propose a robust variance estimator in the Poisson/Cox regression to adjust for over dispersion.…”
Section: The Estimation Methodsmentioning
confidence: 99%
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