Altitudinal patterns for longevity, fecundity and senescence in Drosophila buzzatii

Norry, Fabian M.; Sambucetti, Pablo; Scannapieco, Alejandra Carla; Loeschcke, Volker

doi:10.1007/s10709-005-5537-7

Cited by 42 publications

(51 citation statements)

References 61 publications

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“…D. koepferae is much shorter lived than D. buzzatii not only under standardized laboratory conditions (i.e., common environment, with experimentally removed extrinsic causes of mortality) but also in the wild (Sambucetti et al 2005). In addition, early fecundity is strongly higher in D. koepferae than in D. buzzatii during the first 6 days of age, whereas the opposite pattern of inter-specific variation is found for late fecundity particularly after 11 days of age in all populations studied (Sambucetti et al 2005;Norry et al 2006). In the present study we found that D. koepferae is much more resistant to heat knockdown than D. buzzatii in relatively early but not in later ages.…”

Section: Discussionmentioning

confidence: 93%

Heat-induced hormesis in longevity of two sibling Drosophila species

et al. 2006

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Previous work showed that mild-heat stress induces longevity hormesis in a model organism, D. melanogaster. Here we compared the possible heat-induced hormesis in longevity of other species of Drosophila, D. buzzatii and its sibling species D. koepferae, in a single-sex environment. Possible correlations between longevity and heat-stress resistance were also tested by measuring longevity, heat-knockdown resistance and the heat-induced Hsp70 expression for each species in a common environment. D. buzzatii was longer lived than D. koepferae at benign temperature. Knockdown resistance to heat stress was positively correlated to longevity within species. However, the shorter-lived species was more resistant to knockdown by heat stress than the longer-lived species. The heat-induced Hsp70 expression was similar between species. A heat-shock treatment (37 degrees C for 1 h at 4 days of age) extended mean longevity in the longer lived species but not in the shorter lived species. In D. koepferae, the demographic rate of senescence decreased but the baseline mortality rate increased by heat-shock, resulting in no extension of mean longevity. Sympatric populations of closely related species can be differentially sensitive to temperature and exhibit different patterns of 37 degrees C-induced hormesis in demographic senescence and longevity. The results also show that positive correlations between stress resistance and life span within species can shift in sign across closely related species. Finally, this study shows that heat-induced hormesis in longevity can be found across different Drosophila species, as hormetic effects are not limited to the previously studied D. melanogaster.

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Section: Discussionmentioning

confidence: 93%

Heat-induced hormesis in longevity of two sibling Drosophila species

et al. 2006

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“…Increased adult survival with elevation has been observed in fruit flies (Duyck et al 2010) and is explained by trade-offs between fecundity and longevity (Norry et al 2006) or increasing rates of damage from by-products of metabolism in hot temperatures (Leiser et al 2011). In annual species, however, selection on reproductive schedules may induce the opposite patterns, with accelerated senescence at the completion of reproduction (Tatar et al 1997).…”

Section: Insects and Other Arthropodsmentioning

confidence: 99%

Life-History Responses to the Altitudinal Gradient

Laiolo

Obeso

2017

Advances in Global Change Research

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We review life-history variation along elevation in animals and plants and illustrate its drivers, mechanisms and constraints. Elevation shapes life histories into suites of correlated traits that are often remarkably convergent among organisms facing the same environmental challenges. Much of the variation observed along elevation is the result of direct physiological sensitivity to temperature and nutrient supply. As a general rule, alpine populations adopt 'slow' life cycles, involving long lifespan, delayed maturity, slow reproductive rates and strong inversions in parental care to enhance the chance of recruitment. Exceptions in both animals and plants are often rooted in evolutionary legacies (e.g. constraints to prolonging cycles in obligatory univoltine taxa) or biogeographic history (e.g. location near trailing or leading edges). Predicting evolutionary trajectories into the future must take into account genetic variability, gene flow and selection strength, which define the potential for local adaptation, as well as the rate of anthropogenic environmental change and species' idiosyncratic reaction norms. Shifts up and down elevation in the past helped maintain genetic differentiation in alpine populations, with slow life cycles contributing to the accumulation of genetic diversity during upward migrations. Gene flow is facilitated by the proximity of neighbouring populations, and global warming is likely to move fast genotypes upwards and reduce some of those constraints dominating alpine life. Demographic buffering or compensation may protect local alpine populations against trends in environmental conditions, but such mechanisms may not last indefinitely if evolutionary trajectories cannot keep pace with rapid changes.

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“…It is not surprising that sex influences the lifespan extending effect of hormesis in insects as longevity in males and females respond differently to most genetic or environmental interventions (see, e.g. Maklakov et al 2008Maklakov et al , 2009Bilde et al 2009;Iliadi et al 2009;Tricoire et al 2009) and is even reported to respond differently to clinal selection in the wild (Norry et al 2006). However, in some experiments the hormesis phenomenon has been documented in both sexes (Le Bourg et al 2001;Hercus et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Life extension and the position of the hormetic zone depends on sex and genetic background in Drosophila melanogaster

Sarup

Loeschcke

2010

Biogerontology

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Hormesis, the beneficial effect of a mild stress, has been proposed as a means to prolong the period of healthy ageing as it can increase the average lifespan of a cohort. However, if we want to use hormesis therapeutically it is important that the treatment is beneficial on the individual level and not just on average at the population level. Long lived lines have been shown not to benefit from a, in other lines, hormesis inducing heat treatment in Drosophila melanogaster, D. buzzatii and mice. Also in many experiments hormesis has been reported to occur in one sex only, usually males but not in females. Here we investigated the interaction between the hormetic response and genetic background, sex and duration of a mild heat stress in D. melanogaster, using three replicate lines that have been selected for increased longevity and their respective control lines. We found that genetic background influences the position of the hormetic zone. The implication of this result could be that in a genetically diverse populations a treatment that is life prolonging in one individual could be life shortening in other individuals. However, we did find a hormetic response in all combinations of line and sex in at least one of the experiments which suggests that if it is possible to identify the optimal hormetic dose individually hormesis might become a therapeutic treatment.

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Altitudinal patterns for longevity, fecundity and senescence in Drosophila buzzatii

Cited by 42 publications

References 61 publications

Heat-induced hormesis in longevity of two sibling Drosophila species

Heat-induced hormesis in longevity of two sibling Drosophila species

Life-History Responses to the Altitudinal Gradient

Life extension and the position of the hormetic zone depends on sex and genetic background in Drosophila melanogaster

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