Altruistic Kidney Donation to a Stranger: Psychosocial and Functional Outcomes at Two US Transplant Centers

Rodrigue, James R.; Schutzer, M.E.; Paek, Matthew; Morrissey, Paul

doi:10.1097/tp.0b013e31820dd2bd

Cited by 58 publications

(83 citation statements)

References 12 publications

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“…First, it is possible that donors experience a boost in self-esteem and life satisfaction as result of feelings of pride and positive reactions from the environment right after donation. This was also found in the study by Rodrigue et al (10). This boost could suppress or outweigh psychologic symptoms in the first months after donation.…”

Section: Discussionsupporting

confidence: 54%

“…However, 2 of those 13 donors showed a clinically significant increase. This number corresponds with the percentage of donors who reported that being a donor contributed to anxiety or depression in the earlier mentioned study of Rodrigue et al (10). Also, among specified donors, most studies reveal that a small percentage of the donors show an increase in psychologic symptoms, although the results are, to some extent, conflicting (13).…”

Section: Discussionmentioning

confidence: 78%

“…These studies concluded that most donors reported no psychologic problems after donation, although a few donors reported unexpected stress or that the donation contributed to depression or anxiety (7,8,10).…”

mentioning

confidence: 95%

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Psychologic Functioning of Unspecified Anonymous Living Kidney Donors Before and After Donation

et al. 2013

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We found more increases in psychologic symptoms than decreases, particularly if follow-up time was longer. However, for almost all donors, these increases were not clinically significant and the clinically significant changes found are comparable with natural fluctuations in psychologic symptoms in the general population. Possibly, the donors underreported their psychologic symptoms before donation to pass the screening. Due to the low level of predonation symptoms reported, regression to the mean could also explain the results. Although we found that changes were not associated with donation-related factors, it is possible that other donation-related factors or other life events not measured have an influence on psychologic functioning. Therefore, further research is needed to investigate whether the fluctuations are related to the donation process.

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Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 78%

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Psychologic Functioning of Unspecified Anonymous Living Kidney Donors Before and After Donation

et al. 2013

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“…Since then, many of the recent papers looking at NDDs look only at the data of a single center. In the US, reports have been published from Utah (20 donors), Minnesota (22 donors), and Rhode Island (11 and 39 donors, respectively) [1,[6][7][8]. From abroad, reports from individual centers in Sweden (3 donors), New Zealand (17 donors), and the Netherlands (8 donors) have been published [5,9,11].…”

Section: Recent Ndd Literaturementioning

confidence: 99%

“…-especially in the United States (US). Work that has been done thus far focuses on the experiences of a single center, rather than the country at large [1,[5][6][7][8][9]. To our knowledge, the last scholarly publication looking at national demographic data of NDDs in the US was published in 2003 [10].…”

Section: Introductionmentioning

confidence: 99%

Demographic Characteristics of Non-directed Altruistic Kidney Donors in the United States

DA¹

2016

J Kidney

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Among transplant centers in the US, the acceptance of kidneys from non-directed, altruistic donors is a relatively recent phenomenon, beginning in the late 1990's. Originally starting out as a handful each year, the number of nondirected donations has since increased to now represent over 3% of the annual living donor pool of transplanted kidneys. The psychosocial and functional outcomes of non-directed donors have been extensively studied, yet the demographic characteristics of these donors have largely escaped analysis on a national-level. We examined national UNOS data from the past 27 years to understand the demographic characteristics of non-directed donors by gender, ethnicity, citizenship status, UNOS region, and ABO blood type. In this analysis, we found that: non-directed donors are an increasingly important source of kidneys; non-directed donors have tended to be male, white, and US citizens; several UNOS regions (5, 7, and 9 in particular) are more prolific in performing non-directed donations than others; and non-directed donors are more likely to be of either ABO type O or A. Continued study of this population is needed to understand how these non-directed donor demographic characteristics may change over time.

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Challenging the Traditional Paradigm of Supply and Demand in Pediatric Liver Transplantation Through Nondirected Living Donation: A Case Series

et al. 2021

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A gap exists between the demand for pediatric liver transplantation and the supply of appropriate size-matched donors. We describe our center's experience with pediatric liver transplantation using anonymous nondirected living liver donors (ND-LLD). First-time pediatric liver transplant candidates listed at our center between January 2012 and June 2020 were retrospectively reviewed and categorized by donor graft type, and recipients of ND-LLD grafts were described. A total of 13 ND-LLD pediatric liver transplantations were performed, including 8 left lateral segments, 4 left lobes, and 1 right lobe. Of the ND-LLD recipients, 5 had no directed living donor evaluated, whereas the remaining 8 (62%) had all potential directed donors ruled out during the evaluation process. Recipient and graft survival were 100% during a median follow-up time of 445 (range, 70-986) days. Of ND-LLDs, 69% were previous living kidney donors, and 1 ND-LLD went on to donate a kidney after liver donation. Of the ND-LLDs, 46% were approved prior to the recipient being listed. Over time, the proportion of living donor transplants performed, specifically from ND-LLDs, increased, and the number of children on the waiting list decreased. The introduction of ND-LLDs to a pediatric liver transplant program can expand the benefit of living donor liver transplantation to children without a suitable directed living donor while achieving excellent outcomes for both the recipients and donors.

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Altruistic Kidney Donation to a Stranger: Psychosocial and Functional Outcomes at Two US Transplant Centers

Abstract: Overall, findings indicate that carefully screened ADs experience psychosocial and functional outcomes comparable with those of TDs and should not be systematically excluded from the opportunity to donate.

Cited by 58 publications

References 12 publications

Psychologic Functioning of Unspecified Anonymous Living Kidney Donors Before and After Donation

Psychologic Functioning of Unspecified Anonymous Living Kidney Donors Before and After Donation

Demographic Characteristics of Non-directed Altruistic Kidney Donors in the United States

Challenging the Traditional Paradigm of Supply and Demand in Pediatric Liver Transplantation Through Nondirected Living Donation: A Case Series

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