Aluminum‐containing antiperspirants are not associated with breast cancer

Osto, Muhammad; Farshchian, Mehdi; Alnabolsi, Amira; Smidi, Salam A.; Baiyasi, Maya; Potts, Geoffrey F.

doi:10.1111/jocd.14796

J of Cosmetic Dermatology

2022

DOI: 10.1111/jocd.14796

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Aluminum‐containing antiperspirants are not associated with breast cancer

Muhammad Osto

Mehdi Farshchian

Amira Alnabolsi

et al.

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Cited by 2 publications

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“…Consequently, concerns regarding the potential absorption of aluminum into the human body appear to be unfounded, particularly regarding cancer risks such as breast cancer. Numerous studies have highlighted the safety of antiperspirants (Osto et al, 2022).…”

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confidence: 99%

Are Antiperspirants Safe? Shedding Light on the Distribution of Aluminum Compounds in Sweat Glands

2023

Plastic and Aesthetic Nursing

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The safety of antiperspirants has been a subject of intense debate, with conflicting perspectives and research findings. This study aimed to contribute to the discussion by investigating the distribution of aluminum chloride (AlCl3), a common ingredient in antiperspirants, within the sweat glands. We enrolled a total of 10 patients seeking surgery for bromhidrosis in our study. Before surgery, we instructed the study participants to apply a specially formulated AlCl3 staining antiperspirant to their underarms using a surgical pen with ink that resists easy removal. We excised the apocrine glands, fragmented them finely, and examined them microscopically. We did not detect any stained aluminum compounds. These results are consistent with previous research, which suggests that aluminum compounds do not enter the apocrine glands. Consequently, concerns regarding the potential absorption of aluminum into the human body appear to be unfounded, particularly regarding cancer risks such as breast cancer.

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confidence: 99%

Are Antiperspirants Safe? Shedding Light on the Distribution of Aluminum Compounds in Sweat Glands

2023

Plastic and Aesthetic Nursing

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Exploring the Potential Link between Aluminum-Containing Deodorants/Antiperspirants and Breast Cancer: A Comprehensive Review

Hangan,

Bjorklund,

Chirila

2025

CMC

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The potential association between aluminum-containing deodorants/antiperspirants and breast cancer has been investigated and debated. This paper comprehensively analyzes existing literature to examine the evidence and provide insights into this relationship. This comprehensive review discusses aspects related to the absorption and distribution of aluminum compounds, its effects on the induction of oxidative stress, the estrogenic activity of aluminum, and potential disruption of hormonal pathways, and the potential role in breast cancer induction. Currently, available research, consisting of epidemiological studies as well as clinical trials, together with meta-analyses and previously published reviews conducted on identifying the relationship between aluminum-containing deodorants/antiperspirants and the risk of breast cancer were also analyzed and discussed. Societal factors, personal hygiene considerations, and lifestyle changes contribute to the increased usage of antiperspirants, but they do not establish a direct causal connection with breast cancer. Further research employing larger-scale studies and rigorous methodologies must validate the existing findings and explore the underlying mechanisms involved. Continued multidisciplinary research efforts and collaboration between researchers, regulatory bodies, and public health authorities are vital to developing a more definitive understanding of this complex topic.

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Aluminum‐containing antiperspirants are not associated with breast cancer

Cited by 2 publications

References 6 publications

Are Antiperspirants Safe? Shedding Light on the Distribution of Aluminum Compounds in Sweat Glands

Are Antiperspirants Safe? Shedding Light on the Distribution of Aluminum Compounds in Sweat Glands

Exploring the Potential Link between Aluminum-Containing Deodorants/Antiperspirants and Breast Cancer: A Comprehensive Review

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