1999
DOI: 10.1053/clon.1999.9096
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Alveolar Rhabdomyosarcoma Metastatic to the Breast: Long-Term Survivor

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Cited by 8 publications
(6 citation statements)
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“…Here, we describe a patient with extensive distant metastases, including the breast, hilum, chest wall, lungs, liver, pancreas, peritoneal cavity, and right ovary. Of note, the finding of breast metastases in our patient is concordant with prior studies that have found RMS breast metastases only in female patients with alveolar subtype [14][15][16]. The extent of metastatic disease at the time of diagnosis raises the question of how impactful the month-long delay in diagnosis in terms of disease progression and overall likelihood of survival.…”
Section: Discussionsupporting
confidence: 90%
“…Here, we describe a patient with extensive distant metastases, including the breast, hilum, chest wall, lungs, liver, pancreas, peritoneal cavity, and right ovary. Of note, the finding of breast metastases in our patient is concordant with prior studies that have found RMS breast metastases only in female patients with alveolar subtype [14][15][16]. The extent of metastatic disease at the time of diagnosis raises the question of how impactful the month-long delay in diagnosis in terms of disease progression and overall likelihood of survival.…”
Section: Discussionsupporting
confidence: 90%
“…A possible explanation for this discrepancy is that the feasibility of local retreatment in case of local recurrences may be influenced by the pretreatment, for example, prior radiation. Moreover, RMA can relapse in uncommon sites, such as the breast, which can be treated with surgery and/or radiotherapy . We thus found that the application of the same staging principles as those used at the time of primary diagnosis may serve as a good predictor of post‐relapse outcome regardless of the primary site.…”
Section: Discussionmentioning
confidence: 87%
“…The involvement of breast is rare, the primary involvement being extremely rare. [ 2 3 4 5 6 7 8 ] In a series reported from an intergroup RMS study, of the total 26 patients described, 19 had metastatic disease and the remaining 7 had primary disease in the breast. Alveolar histology was common and was seen in 24 patients and embryonal variant was seen in 1 patient.…”
Section: Discussionmentioning
confidence: 99%