Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix

Abstract

PurposeThe aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically.MethodsOverall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure.ResultsClinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue.ConclusionsSocket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period.

Alveolar ridge preservation and early implant placement at maxillary central incisor sites: A prospective case series study

“…Although fully epithelialized, the soft tissue invagination observed at 9/10 cases after 8-10 weeks of healing indicates that the mucosa had not fully healed. This is consistent with a clinical study that used a soft tissue healing index to evaluate the healing extraction sockets with CM placed over DBBMC in seven patients (Maiorana et al, 2017). At 4 weeks, there were no sites that had completely healed, whereas at 8 weeks, 5/7 sites had healed completely.…”

“…In the present study, CM was placed over the DBBMC to provide an initial barrier and to subsequently promote soft tissue closure over the socket. The CM undergoes a substitution process and is replaced with a vascularized collagen-rich connective tissue (Maiorana et al, 2017). Although fully epithelialized, the soft tissue invagination observed at 9/10 cases after 8-10 weeks of healing indicates that the mucosa had not fully healed.…”

Alveolar ridge preservation in the posterior maxilla reduces vertical dimensional change: A randomized controlled clinical trial

“…Alveolar ridge preservation (ARP) is considered to be a valid therapeutic option since it significantly reduces the dimensional changes of the ridge post‐extraction (Avila‐Ortiz, Elangovan, Kramer, Blanchette, & Dawson, ; Choi et al, ; Maiorana et al, ). Previous data suggested that ARP may prevent the pneumatization process and reduce the need for subsequent sinus augmentation at implant placement in the posterior region (Levi, Halperin‐Sternfeld, Horwitz, Zigdon‐Giladi, & Machtei, ; Rasperini, Canullo, Dellavia, Pellegrini, & Simion, ).…”

Tunnel’ radicular cyst and its management with root canal treatment and periapical surgery: A case report

“…Bone grafts will also act as an osteoconductive material to stabilize blood clot and advance bone regeneration by providing a scaffold, thus enhancing the migration of osteoprogenitor cells. [12][13][14] Our patient had received xenograft bone Osteo-LEMB to restore the defective site since the technique was well accepted by him and does not contravene his faith and beliefs. Active and fast proliferation of the soft tissue from the buccal, lingual and palatal aspects may interfere with the bone ingrowth from approximal bone surfaces which result in a fibrous connective tissue core.…”