Alvéolite aiguë après utilisation d'un aérosol imperméabilisant : à propos de deux observations

Testud, F.; Gabrielle, L; Paquin, ML; Descotes, Jacques

doi:10.1016/s0248-8663(97)89328-9

Cited by 13 publications

(12 citation statements)

References 6 publications

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“…As reported in previously published observations [2,7,18], influenza-like symptoms often accompany acute respiratory symptoms and are similar to those observed in polymer fume fever. In patient 2, heat decomposition products of the fluoro-resin, resulting from cigarette smoking with spray-contaminated fingers during or just after coating, might have led to worsening of symptoms.…”

Section: Discussionsupporting

confidence: 87%

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Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland

Lazor-Blanchet

Rusca

Vernez

et al. 2004

International Archives of Occupational and Environmental Health

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Section: Discussionsupporting

confidence: 87%

“…Numerous cases of respiratory failure following indoor, but also outdoor, use of waterproofing sprays have been reported in Europe [18,21,23], North America [1] and Japan [17] in the past two decades. These outbreaks of respiratory illness occurred following a formulation change.…”

Section: Introductionmentioning

confidence: 99%

Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland

Lazor-Blanchet

Rusca

Vernez

et al. 2004

International Archives of Occupational and Environmental Health

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“…Inhalational lung injury from water repellent spray has rarely been described and only in case report form [1,2,3,4]. Characteristic features of the previous reports are massive exposure in poorly ventilated areas and in two cases the proposed additional thermal-mediated degradation products of fluorochemicals [2, 3].…”

Section: Discussionmentioning

confidence: 99%

Hill Walkers’ Lung

Cormican

Rees²

2006

Respiration

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A previously healthy female presented with a 7-week history of dyspnoea on exertion following inhalation of a fluorochemical-based water repellent spray, which was applied to footwear, in the living area that she shared with 8 members of her family while on a hill walking holiday. Clinical examination, serial lung function studies, bronchoalveolar lavage, transbronchial biopsies and high-resolution CT thorax confirmed a sub-acute interstitial pneumonitis, which did not resolve until 15 weeks following exposure. None of her family members were affected despite similar exposure. Interstitial pneumonitis due to inhalation of fluorochemical-based water repellent, though rarely described, usually presents in an acute severe form necessitating immediate therapy and resolves in 1–4 weeks. Pulmonary fibrosis can also occur. Sub-acute interstitial pneumonitis following inhalation of fluorochemical-based water repellent spray should always be considered as a cause of unexplained persistent respiratory symptoms in otherwise healthy individuals involved in outdoor pursuits.

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“…effects of water repellents' inhalation have been reported [1][2][3][4][5][6][7][8][9]. Our case showed an extremely negative and aggressive impact, probably because of the pre-existing and misdiagnosed IPF.…”

Section: Discussionmentioning

confidence: 78%

“…The patient's respiratory conditions seemed to saturation -82%, heart rate -115 beats per min, blood pressure -115/80 mm Hg). Arterial blood gas analysis showed severe hypoxemia and respiratory alkalosis (pH = 7.5, partial pressure of carbon dioxide (pCO 2 the patient's respiratory conditions continued to deteriorate and 87 days after the aerosolized water repellent's inhalation, the patient died from a respiratory failure.…”

Section: Introductionmentioning

confidence: 99%

Acute exacerbation of idiopathic pulmonary fibrosis after inhalation of a water repellent

Bennett¹,

Bargagli²,

Refini³

et al. 2015

Int J Occup Med Environ Health

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The natural course of idiopathic pulmonary fibrosis (IPF) is unpredictable at the time of diagnosis. Some patients may experience episodes of acute respiratory worsening that have been termed acute exacerbations. A 58-year-old male was admitted to our Emergency Department due to progressive and intense dyspnea and dry cough after accidental inhalation of waterproof's vapor containing siloxanes. Chest high resolution computed tomography (HRCT) scan showed diffuse and bilateral ground glass attenuation, basal predominant reticular abnormalities and subpleural honeycombing. The patient didn't know that he suffered from IPF and siloxanes' inhalation triggered an acute exacerbation of his disease. Clinical course after the inhalation was aggressive and, despite steroids and cyclophosphamide therapy, the patient died 3 months after due to a respiratory failure. Inhalation of water repellents has been associated with an acute onset of respiratory symptoms and acute lung injury; usually, however, the prognosis is commonly good with a complete recovery. Our case is an example of an extremely negative reaction probably because of pre-existing and misdiagnosed IPF. Currently, no literature concerning water repellent inhalation as a trigger of acute exacerbation of IPF is available.

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Alvéolite aiguë après utilisation d'un aérosol imperméabilisant : à propos de deux observations

Cited by 13 publications

References 6 publications

Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland

Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland

Hill Walkers’ Lung

Acute exacerbation of idiopathic pulmonary fibrosis after inhalation of a water repellent

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