Alzheimer’s Disease and Related Dementias Diagnosis in the United States Among US-Born and Foreign-Born White, Black, Hispanic, and Asian Older Adults

Kindratt, Tiffany B.; Zahodne, Laura B.; Dallo, Florence J.; Ajrouch, Kristine J.

doi:10.1007/s40615-024-02014-z

J. Racial and Ethnic Health Disparities

2024

DOI: 10.1007/s40615-024-02014-z

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Alzheimer’s Disease and Related Dementias Diagnosis in the United States Among US-Born and Foreign-Born White, Black, Hispanic, and Asian Older Adults

Tiffany B. Kindratt,

Laura B. Zahodne,

Florence J. Dallo

et al.

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2024

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Cited by 2 publications

References 34 publications

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What Increase Chance of Dementia among Asian Americans? Analysis of Nativity and Life Course Factors

Okada,

Yang,

et al. 2024

Preprint

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Objectives The Alzheimer’s Association has reported a 746% increase in dementia-related deaths in Asian American populations between 2000 and 2018, the most significant rise compared to all other racial groups. Asian Americans face a unique myriad of obstacles and factors contributing to significant health disparities, including those in dementia. Our aim is to compare determinants and outcomes of dementia between US-born and foreign-born Asian Americans. Methods Data from the 2019–2022 National Health Interview Survey was analyzed to examine the relationship between nativity and dementia. Other life course risk factors and outcomes of having dementia were also included in the analysis. The study sample included 16,331 US-born and 126,978 foreign-born Asian Americans. Results Foreign-born Asian Americans were found to have a higher proportion of dementia compared to US-born Asian Americans (1.1%>0.4%, p = 0.0140). Risk factors that were found to significantly mediate the relationship between nativity and dementia included age > 65, ever being married, having some college education, and having Medicaid coverage. Foreign-born Asian Americans with dementia are more likely to suffer from depression (p < 0.001) and experience/have difficulty in social involvement (p < 0.001) compared to US-born Asian Americans with dementia. Discussion Our findings reaffirm that nativity contributes to the heterogeneous risk and outcomes of dementia in Asian Americans and the likelihood of having dementia is further mediated by life course factors. Interventions to support Asian American immigrants are needed to reduce the burden of dementia. More studies that identify nativity variations are also recommended to address health disparities that disproportionately affect older immigrants.

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What Increase Chance of Dementia among Asian Americans? Analysis of Nativity and Life Course Factors

Okada,

Yang,

et al. 2024

Preprint

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Alzheimer's Disease and Related Dementia among Black Adults Stratified by Nativity

Sorkpor,

Yang,

Lane

et al. 2024

Preprint

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Purpose: To explore ADRD prevalence by nativity, comparing US-born and non-US-born Black individuals to uncover risk factor differences and inform targeted interventions. Methods: We conducted a retrospective cohort study with 77,069 Black individuals from the All of Us Research Program. We analyzed two cohorts, US-born and non-US-born individuals with ADRD, using 1:1 propensity score matching to balance key factors. Analyses were performed in R and Python with significance set at α = 0. 05. Results: Of 72,311 US-born and 4,758 non-US-born Black individuals, 1:1 propensity score matching resulted in 4,758 matched participants per group. ADRD prevalence was 3.76% in US-born and 4.12% in non-US-born Blacks, with rates increasing with age and being higher among retirees and the unemployed. Conclusion: Non-US-born Black individuals have a higher ADRD risk than US-born Blacks due to socioeconomic and demographic factors, supporting the need for targeted interventions and further research to address health inequities.

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Alzheimer’s Disease and Related Dementias Diagnosis in the United States Among US-Born and Foreign-Born White, Black, Hispanic, and Asian Older Adults

Cited by 2 publications

References 34 publications

What Increase Chance of Dementia among Asian Americans? Analysis of Nativity and Life Course Factors

What Increase Chance of Dementia among Asian Americans? Analysis of Nativity and Life Course Factors

Alzheimer's Disease and Related Dementia among Black Adults Stratified by Nativity

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