Alzheimer’s Disease: Exploring the Landscape of Cognitive Decline
Rumiana Tenchov,
Janet M. Sasso,
Qiongqiong Angela Zhou
Abstract:Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. The pathology of AD is marked by the accumulation of amyloid beta plaques and tau protein tangles in the brain, along with neuroinflammation and synaptic dysfunction. Genetic factors, such as mutations in APP, PSEN1, and PSEN2 genes, as well as the APOE ε4 allele, contribute to increased risk of acquiring AD. Currently available treatments provide symptomatic rel… Show more
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