Alzheimer’s Disease Research: Scientific Productivity and Impact of the Top 100 Investigators in the Field

Abstract

Abstract. The online availability of scientific-literature databases and natural-language-processing (NLP) algorithms has enabled large-scale bibliometric studies within the field of scientometrics. Using NLP techniques and Thomson ISI reports, an initial analysis of the role of Alzheimer's disease (AD) within the neurosciences as well as a summary of the various research foci within the AD scientific community are presented. Citation analyses and productivity filters are applied to post-1984, AD-specific subsets of the PubMed and Thomson ISI Web-of-Science literature bases to algorithmically identify a pool of the top AD researchers. From the initial pool of AD investigators, top-100 rankings are compiled to assess productivity and impact. One of the impact and productivity metrics employed is an AD-specific H-index. Within the AD-specific H-index ranking, there are many cases of multiple AD investigators with similar or identical H-indices. In order to facilitate differentiation among investigators with equal or near-equal H indices, two derivatives of the H-index are proposed: the Second-Tier H-index and the Scientific Following H-index. Winners of two prestigious AD-research awards are highlighted, membership to the Institute of Medicine of the US National Academy of Sciences is acknowledged, and an analysis of highly-productive, high-impact, AD-research collaborations is presented.

Mapping the landscape of cerebral amyloid angiopathy research: an informetric analysis perspective

“…Despite its wide application in other research domains, including stroke8 and Alzheimer's disease,9 10 to the best of our knowledge, there have been no previous studies of informetrics or bibliometrics in the field of CAA. The aim of our study is to analyse the research output in the field of CAA over six decades from 1954 to 2014 using advanced informetrics methods, including productivity analysis, network and content analysis, and copublication networks.…”

Preface for the Special Issue of Neuromolecular Medicine in Memory of the Life and Legacy of William R. Markesbery, M.D.

“…That he was recognized in 2009 by the National Alzheimer's Association with the Zavan Khachaturian Award for Outstanding Achievements in Advancing Alzheimer's Science, and that he was named the 23rd most influential researcher in the world in the field of AD research (Sorensen 2009) are additional evidences that his peers in the AD research community tremendously valued his contributions to the better understanding of the molecular basis of AD. And, from my 35 years of deep friendship and collaboration with Bill, I can attest to the accuracy of the statement that Bill was always happy to be at the bench doing research (Fig.…”

A Bibliometric Assessment of Global Ice Bucket Challenge (Amyotrophic Lateral Sclerosis) Research

“…These studies appear in different journals, dedicated to publish research related to neurology. In recent years, various researches on neurological disorder have been analyzed using the bibliometric methods, such as the publication output on Parkinson's disease [8][9][10] , Alzheimer's disease [11][12][13][14] , and Guillain-Barre syndrome [15] . Some other bibliometric studies related to these diseases are specialty focused on the contribution by specific countries [16,17] .…”