Alzheimer’s the Road Ahead in the Middle East

Abyad, Abdulrazak

doi:10.4172/2161-0460.1000241

Cited by 5 publications

(12 citation statements)

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“…Disabled and vulnerable older adults are often cared for by family (Abyad, 2015; Halabi & Zafar, 2010), as it is important to value older adults’ autonomy and dignity (Bentwich et al, 2018). Commonly, older adults in the EM region are primarily supported emotionally and socially by their families, often tribal, and few live alone (Amr et al, 2014; Halabi & Zafar, 2010; Sayegh et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

“…Commonly, older adults in the EM region are primarily supported emotionally and socially by their families, often tribal, and few live alone (Amr et al, 2014; Halabi & Zafar, 2010; Sayegh et al, 2013). If an older adult needs assistance, the family will typically hire a caregiver or a nurse at home; if the family cannot afford a caregiver or nurse, the older adult must remain in the care of his or her relatives (Abyad, 2015; Alabed et al, 2014; Halabi & Zafar, 2010). Introducing the older person to a care facility is considered abandonment of a family duty, which is unacceptable.…”

Section: Resultsmentioning

confidence: 99%

“…Introducing the older person to a care facility is considered abandonment of a family duty, which is unacceptable. Consequently, the EM region has few care facilities (Abyad, 2015; Alsenany & Alsaif, 2012; Amr et al, 2014; Halabi & Zafar, 2010; Sayegh et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

“…Studies indicated a lack of published data on dementia incidence and prevalence, as well as inconsistencies among published studies regarding dementia prevalence in the EM region (Sharifi et al, 2014). Older adults in the EM are insufficiently studied, and no baseline data are available for dementia (Abyad, 2015; Afgin et al, 2012; Alaama, 2016; Almodeer et al, 2013; Werner et al, 2015).…”

Section: Discussion and Recommendation For Future Studiesmentioning

confidence: 99%

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Dementia in Eastern Mediterranean countries: A systematic review

2018

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Globally, there is an increase in the older population, whose lives are affected by local cultural norms. In Eastern Mediterranean countries, dementia is conventionally hidden from view with few dedicated services or recognition for diagnosis. The aim of this systematic review is to explore the limited literature on dementia and cognitive impairment among older people in Eastern Mediterranean countries to present an evaluation of current practices and to consolidate knowledge for future planning. Thirty-three studies were identified for inclusion in the review, and four themes were apparent. Firstly, prevalence, comorbidity and gender: In Eastern Mediterranean countries, many studies identify that the prevalence of dementia is high. As is the case elsewhere, many older adults in Eastern Mediterranean countries have at least one coexisting long-term condition, and some experience low life-satisfaction. Secondly, culture: In Eastern Mediterranean countries, the older adult is highly respected, and placement outside of the family home is considered an abandonment of family duty. The term dementia carries stigma, and it is widely believed that dementia is caused by 'fate'. Thirdly, recognition and tools: There is a lack of verified assessment instruments to assess for dementia. Despite concerns about the cultural appropriateness of the Mini-Mental State Exam, particularly for people who have low literacy levels, and low literacy being the norm in Eastern Mediterranean countries, the Mini-Mental State Examination is the main assessment instrument. Translation and transition of non-Arabic assessment instruments and tools with psychometric properties presents a challenge for clinicians. Finally, workforce issues: health care workers lack knowledge about dementia, as dementia care is a relatively recent addition to the nursing and medical syllabi. While there were some inconsistencies in the papers published, many of the articles call for increasing educational programmes and health and social care policies to promote improved and practical gerontological nursing and medicine. Health care professionals need education about sociocultural, religious, and language needs to deliver improved culturally sensitive care.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussion and Recommendation For Future Studiesmentioning

confidence: 99%

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Dementia in Eastern Mediterranean countries: A systematic review

2018

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“…According to AD association (2020), 10% of the American population age 65 and older has Alzheimer’s dementia ( Jayaraj et al, 2020 ). In the United Arab Emirates, it is reported that AD affect one every seven people with age over 60 years old ( Abyad, 2016 ). The risk of AD is exponentially rise with age to affect one every three people with age over 85 ( Abyad, 2016 ; Jayaraj et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Melatonin and Exercise on Social Isolation-Related Behavioral Changes in Aged Rats

Alghamdi

2022

Front. Aging Neurosci.

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Social isolation (SI) is well established as an environmental factor that negatively influences different behavioral parameters, including cognitive function, anxiety, and social interaction, depending on the age of isolation. Aging is a physiological process that is associated with changes in cognitive function, locomotor activity, anxiety and emotional responses. Few studies have investigated the effect of SI in senescence, or possible interventions. In the current study, we investigated the possible complementary effects of melatonin (MLT) and exercise (Ex) in improving SI-related behavioral changes in aged rats. Forty aged Wistar rats (24 months old) were randomly divided into five groups (n = 8 per group): Control (group housing), SI (individual housing for 7 weeks), SI + MLT (SI rats treated with 0.4 mg MLT/ml in drinking water), SI + Ex (SI rats treated with 60 min of swimming), and SI + MLT + Ex (SI rats treated with both MLT and Ex). Different behavioral tasks were conducted in the following sequence: open field test, elevated plus maze test, sucrose preference test, Y maze test, and Morris water maze test. Locomotor activities measured by total distance moved and velocity revealed that SI + Ex (P = 0.0038; P = 0.0015) and SI + MLT + Ex (P = 0.0001; P = 0.0003) significantly improved the locomotor activity compared with SI rats but SI + MLT (P = 0.0599; P = 0.0627) rats showed no significant change. Anxiety index score was significantly improved in SI + MLT + Ex (P = 0.0256) compared with SI rats while SI + MLT (P > 0.9999) and SI + Ex (P = 0.2943) rats showed no significant change. Moreover, latency to reach the platform in Morris water maze was significantly reduced at day 5 in SI + MLT + Ex (P = 0.0457) compared with SI rats but no change was detected in SI + MLT (P = 0.7314) or SI + Ex (P = 0.1676) groups. In conclusion, this study supports the possible potential of MLT in combination with Ex in improving physical activity, anxiety, and cognitive functions in aging population.

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