Alzheimers Disease-Like Neuropathology Following Exposure to Ambient Noise

Abstract

Many factors play a role in the risk of dementia, including the environment. Widespread and significant worldwide exposure to noise, the severity of related health consequences, and the limited tools available to the public to protect themselves strongly support the WHO's argument that 'noise pollution is not only an environmental nuisance but also a threat to public health'. Exposures to noise from industrial activities, airport noise, or occupational noise are very important. One of the limitations of such studies is the lack of information about lifestyle habits that can play a key role in a person's risk of dementia. This review suggests that people with more exposure to ambient noise are at higher risk of Alzheimer’s Disease (AD) and dementia than other people and we examined how chronic noise exposure causes neuropathology such as AD and how it relates to ApoE4 activation. Further studies are essential to expanding global knowledge about the harmful health effects and costs of health care due to noise pollution.

Neuroprotective Effects of Thiazolidine-4-Carboxylic Acid Derivatives on Memory Impairment and Neurodegeneration

“…Behavioral and cognitive alteration by ethanol consumption in humans is replicated in animal rodent models [42].…”

CNS Demyelination Diseases Following Exposure to Urban Air Pollution

“…The WHO reported that exposure to air pollution is responsible for around 7 million deaths per year [1]. Exposure to air pollution has previously has been characterized to contribute to detrimental CNS occurrences such as neuroinfl ammation, neurodegeneration, and stroke [2][3][4]. While a variety of environmental factors are involved in neuronal infl ammation leading to CNS disease, air pollutants may be the most common source of environmental oxidative stress and infl ammation.…”

The Association Between Stress-Related of COVID-19 Pandemic and Mental Health

“…COVID-19 is a severe respiratory infection, so particles from the breath and speech may contain the virus. Our previous fi ndings show that particulate matter and airborne particles reach the brain and aff ect the health of the Central Nervous System (CNS), and may cause various neuropsychological and pathological disorders [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. In addition, in line with global regulations, governments enacted public health regulations, including mandatory quarantine, social exclusion, and job quarantine, in an eff ort to limit the prevalence of COVID-19 [19].…”