Amanita fuliginea poisoning with thrombocytopenia: A case series

Wang, Qiang; Sun, Meifeng; Lv, Hailin; Peng, Lu; Ma, Chunsheng; Lei, Yang; Li, Shuqin; Tong, Haiqing; Hu, Zhao; Gao, Yanxia

doi:10.1016/j.toxicon.2019.12.156

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…An increasing knowledge of how mushrooms grow has led to the cultivation of over 90 species (Boa, 2004), of which around 30 are grown commercially for food and consumed widely (Chang & Miles, 2004). The remaining cultivated species are grown for medicinal purposes (Lu, Lou, Hu, Liu, & Chen, 2020;Ma et al, 2018;Roncero-Ramos & Delgado-Andrade, 2017;Yang, Belwal, Devkota, Li, & Luo, 2019), as functional foods (Jabłońska-Ryś, Skrzypczak, Sławińska, Radzki, & Gustaw, 2019;Reis, Martins, Vasconcelos, Morales, & Ferreira, 2017) and extracts used as food additives (Hadar & Dosoretz, 1991;Sun et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Reviewing the world's edible mushroom species: A new evidence‐based classification system

Yang

Menolli

et al. 2021

Comp Rev Food Sci Food Safe

135

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Wild mushrooms are a vital source of income and nutrition for many poor communities and of value to recreational foragers. Literature relating to the edibility of mushroom species continues to expand, driven by an increasing demand for wild mushrooms, a wider interest in foraging, and the study of traditional foods. Although numerous case reports have been published on edible mushrooms, doubt and confusion persist regarding which species are safe and suitable to consume. Case reports often differ, and the evidence supporting the stated properties of mushrooms can be incomplete or ambiguous. The need for greater clarity on edible species is further underlined by increases in mushroom‐related poisonings. We propose a system for categorizing mushroom species and assigning a final edibility status. Using this system, we reviewed 2,786 mushroom species from 99 countries, accessing 9,783 case reports, from over 1,100 sources. We identified 2,189 edible species, of which 2,006 can be consumed safely, and a further 183 species which required some form of pretreatment prior to safe consumption or were associated with allergic reactions by some. We identified 471 species of uncertain edibility because of missing or incomplete evidence of consumption, and 76 unconfirmed species because of unresolved, differing opinions on edibility and toxicity. This is the most comprehensive list of edible mushrooms available to date, demonstrating the huge number of mushrooms species consumed. Our review highlights the need for further information on uncertain and clash species, and the need to present evidence in a clear, unambiguous, and consistent manner.

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Section: Introductionmentioning

confidence: 99%

Reviewing the world's edible mushroom species: A new evidence‐based classification system

Yang

Menolli

et al. 2021

Comp Rev Food Sci Food Safe

135

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“…The median platelet concentrations in these cases were 87 (39–139) ×10 9 /L, which is in line with the results from the current study. A recent case series, describing the outcome of three cases of Amanita fuliginea poisoning, also described thrombocytopenia as a potential complication [ 31 ]. As this mushroom also contains amatoxins and virotoxins, the underlying mechanisms may be similar.…”

Section: Discussionmentioning

confidence: 99%

Unexpected Amanita phalloides-Induced Hematotoxicity—Results from a Retrospective Study

Visser,

Hof,

Broek

et al. 2024

Toxins

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Introduction: Amanita phalloides poisoning is a serious health problem with a mortality rate of 10–40%. Poisonings are characterized by severe liver and kidney toxicity. The effect of Amanita phalloides poisonings on hematological parameters has not been systematically evaluated thus far. Methods: Patients with suspected Amanita phalloides poisonings were retrospectively selected from the hospital database of the University Medical Center Groningen (UMCG). Medical data—including demographics; liver, kidney, and blood parameters; treatment; and outcomes—were collected. The severity of the poisoning was scored using the poison severity score. Results: Twenty-eight patients were identified who were admitted to the UMCG with suspected Amanita phalloides poisoning between 1994 and 2022. A time-dependent decrease was observed for hemoglobin and hematocrit concentrations, leukocytes, and platelets. Six out of twenty-eight patients developed acute liver failure (ALF). Patients with ALF showed a higher increase in liver enzymes, international normalized ratios, and PSS compared to patients without ALF. Conversely, hemoglobin and platelet numbers were decreased even further in these patients. Three out of six patients with ALF died and one patient received a liver transplant. Conclusion: Our study shows that Amanita phalloides poisonings may be associated with hematotoxicity in patients. The quantification of hematological parameters is of relevance in intoxicated patients, especially in those with ALF.

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“…Wang et al [32] In China, there have been three cases of severe thrombocytopenia brought on by A. fuliginea poisoning. After ingesting wild A. fuliginea, three patients experienced nausea, vomiting, stomach discomfort, and diarrhea.…”

Section: Xu Et Al [31]mentioning

confidence: 99%

Mushroom Poisoning: A Case Series With a Literature Review of Cases in Asia Region

Vaibhav,

Meshram,

et al. 2023

Cureus

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Mushroom is a fungus widely used as an edible in various parts of the world, especially in hilly regions with damp climates. Nevertheless, when picked from the wild to use as a vegetable, it has proved fatal for people ingesting it due to a lack of knowledge for distinguishing between poisonous and non-poisonous mushrooms by the people of the local community. Three cases presented as emergencies from a single household comprising a 13-year-old girl and both her grandparents following the ingestion of mushrooms picked from a nearby forest area. Luckily the parents of the girl were out for work, so they survived and helped identify the mushroom. Most cases are not reported or documented, and data are present mainly in the form of case reports.

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Amanita fuliginea poisoning with thrombocytopenia: A case series

Cited by 6 publications

References 10 publications

Reviewing the world's edible mushroom species: A new evidence‐based classification system

Reviewing the world's edible mushroom species: A new evidence‐based classification system

Unexpected Amanita phalloides-Induced Hematotoxicity—Results from a Retrospective Study

Mushroom Poisoning: A Case Series With a Literature Review of Cases in Asia Region

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