Compared with the diagnostic criteria of Disruptive Mood Dysregulation Disorder (DMDD) and research on comorbidities, research on the treatment of DMDD is scarce. Since it was defined in 2012, children have been diagnosed with DMDD every year. They lose their temper frequently and severely and impair their daily lives. This article aims to review and summarize the relevant information of DMDD and focuses on treatment methods. The review includes drug treatment and psychotherapy. Drug treatment is divided into antidepressants, mental stabilizers, antipsychotics, and some other drugs. Although there are many treatments for the core symptom of DMDD, which is severe irritability, research is limited by insufficient samples due to low prevalence. Nevertheless, clinicians, psychologists, and scholars should continue to pay attention to the treatment of DMDD.