Amaurotic Idiocy and Related Conditions*

Heredodegenerations and Heredoconstitutional Defects of the Retina

“…They have been found by Hagedoorn (1940) and by MacMillan (1948) in the cells of the inner nuclear layer. The changes in the glia and mesenchymal cells are secondary.…”

Ocular Manifestations in Tay‐sachs‘ and Niemann‐pick's Diseases

“…I n the swollen ganglion cells, the nucleus is located eccentric and the cytoplasm often shows a vacuolated appearance. Atrophy of the optic nerve and the nerve fibre layer is also often described (Hagedoorn 1940, PoStiC 1949, Dolcet-Bzcxerds 1950. It is only re- cently that attemps have been made to investigate the deposited lipids histochemically (Greenfield 1951, Cogan & Kuwabara 1959.…”