Amazonian <i>Eryngium foetidum</i> leaves exhibited very high contents of bioactive compounds and high singlet oxygen quenching capacity

Leitão, Deusa do Socorro Teixeira Costa; Siqueira, Francilia Campos de; Sousa, Sérgio Henrique Brabo de; Mercadante, Adriana Zerlotti; Chisté, Renan Campos

doi:10.1080/10942912.2020.1811311

Cited by 20 publications

(22 citation statements)

References 40 publications

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“…In our study, both the extracts of A. amazonicum fruits showed high efficiency as źO 2 quencher; however, the peel extract was almost five times more efficient (IC 50 = 16 µg/mL) than the pulp one (IC 50 = 76 µg/ml; Figure 2c). These extracts exhib-ited higher 1 O 2 -quenching capacity than other extracts also reported as efficient 1 O 2 -quenchers, such as the extracts with high contents of bioactive compounds obtained from leaves of Arrabidaea chica (IC 50 = 177 µg/ml; De Siqueira et al, 2019) and Eryngium foetidum (IC 50 = 343 µg/ml; Leitão et al, 2020). The inhibition of oxidative damage mediated by 1 O 2 is of paramount importance in food systems for inhibiting or delaying important oxidative reactions, such as lipid peroxidation (Choe & Min, 2006), but also in physiological systems, since excessive generation induces redox imbalance in cell physiology, causing many disorders and diseases (Schweitzer & Schmidt, 2003).…”

Section: Scavenging Capacity Of Peel and Pulp Extracts Of A Amazonicum Fruitsmentioning

confidence: 91%

Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species

Barbosa-Carvalho

Leitão

Siqueira

et al. 2021

Journal of Food Science

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Antrocaryon amazonicum fruits are unexploited sources of bioactive compounds found in the Amazonia region of Brazil. In this study, for the first time, the carotenoid and phenolic compound profiles of the pulp and peel of A. amazonicum fruits, from two varieties at two harvest periods, were determined by LC-MS. Additionally, the potential of the peel and pulp extracts to scavenge physiologically relevant reactive oxygen species (ROS) and reactive nitrogen species (RNS) was assessed. The major carotenoids in both parts of the fruits were lutein, accounting for ≈42% of the identified carotenoids in the peel and ≈25% in the pulp, whereas catechin and hydroxybenzoic acid derivatives were the major phenolics in both parts. The peel extract, which presented the highest bioactive compound contents, was more efficient to scavenge ROS than the pulp.The peel extract showed high scavenging efficiency (IC 50 ) for singlet oxygen ( 1 O 2 ; 16 µg/ml), hypochlorous acid (HOCl; 20 µg/ml), peroxynitrite (ONOO -; 38 µg/ml), and superoxide radical (O 2•-; 47 µg/ml), whereas the pulp extract exhibited high efficiency for ONOO -(13 µg/ml), followed by HOCl (30 µg/ml), źO 2 (76 µg/ml), and less efficient for O 2 •-(44 µg/ml). Therefore, A. amazonicum fruits can be seen as an expressive source of bioactive compounds with high antioxidant potential to be further investigated to inhibit or delay oxidative processes both in food and physiological systems triggered by ROS and RNS. Practical Application: Bioactive compound extracts of Antrocaryon amazonicum fruits have high potential to be exploited for inhibiting or delaying oxidative processes and increase food stability.

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Section: Scavenging Capacity Of Peel and Pulp Extracts Of A Amazonicum Fruitsmentioning

confidence: 91%

Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species

Barbosa-Carvalho

Leitão

Siqueira

et al. 2021

Journal of Food Science

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“…In this sense, studies have analyzed the applications of E . foetidum and have pointed to its pharmacological potential, notably Bhavana et al [ 3 ], Forbes et al [ 13 ], Sumitha et al [ 14 ], and Leitão et al [ 15 ], confirming the bioactive and antioxidant potential of this plant.…”

Section: Introductionmentioning

confidence: 94%

“…Some essential oils are products of secondary metabolism, normally produced by aromatic plants. They are defined as complex mixtures and have high added value due to their applications in the pharmaceutical industry [ 5 , 15 ].…”

Section: Chemical Profilementioning

confidence: 99%

“…ey are defined as complex mixtures and have high added value due to their applications in the pharmaceutical industry [5,15]. e chemical profile of the essential oils from E. foetidum is characterized by aromatic and aliphatic aldehydes.…”

Section: Volatile Fixedmentioning

confidence: 99%

“…is species is also used in ethnomedicine, since it has shown potential application in diseases related to the gastrointestinal tract and acts as an antibacterial, analgesic, anti-inflammatory, anthelmintic, anticonvulsant, and anticancer agent, thus proving to have great ethnopharmacological importance for people [10][11][12]. In this sense, studies have analyzed the applications of E. foetidum and have pointed to its pharmacological potential, notably Bhavana et al [3], Forbes et al [13], Sumitha et al [14], and Leitão et al [15], confirming the bioactive and antioxidant potential of this plant.…”

Section: Introductionmentioning

confidence: 99%

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Eryngium foetidum L. (Apiaceae): A Literature Review of Traditional Uses, Chemical Composition, and Pharmacological Activities

Rodrigues

Silva

Gurgel

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Eryngiumfoetidum L. is popularly known as chicória-do-Pará, is native to the Amazon region, and is widely distributed in Northern Brazil. It is considered a versatile species due to its diversified uses in ethnomedicine, gastronomy, and pharmaceutical industry. The objective of this study was to review the literature on the traditional uses, chemical composition, and pharmacological activities of E. foetidum based on information published in national and international scientific articles between the years 2011 and 2021. Literature searches were performed with the combination of the expressions “Eryngium foetidum L.,” “chicória-do-Pará,” “traditional uses,” “ethnobotany,” “volatile compounds,” and “essential oil.” The species is widely used as a flavoring condiment in beans, meat, duck, and fish, and in the preparation of tucupi (cassava sap), showing to have great importance for the Amazonian food culture. In traditional medicine, it has analgesic, antibacterial, antiflu, and antipyretic applications. The chemical profile is characterized by the presence of aromatic and aliphatic aldehydes, mainly (2E)-2-dodecenal in leaves and 2,3,4-trimethylbenzaldehyde in roots, in addition to fixed compounds such as carotenoids, flavonoids, and phenols. These compounds have shown diverse biological activities and potential antibacterial, anthelmintic, and antioxidant applications, confirming their potential for use in folk medicine. Therefore, it is inferred that this aromatic plant has vast potential uses and is an important alternative as a natural resource for the food and pharmaceutical industries in view of its antioxidant capacity and bioactive compounds.

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Little-known Saniculeae genera: phytochemical studies and pharmaceutical activities

Kikowska,

Hermosaningtyas,

Chanaj-Kaczmarek

2024

Phytochem Rev

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This work initiates the original and updated literature review of the current state of research on the Saniculoideae subfamily, emphasizing the selected genera Saniculeae, namely Sanicula, Hacquetia, Astrantia, and Eryngium. Various parts of these plants, especially aerial parts and roots, have an immense range of medicinal uses in traditional medicine for a number of ailments. Phytochemical studies conducted on the Saniculeae species indicate that these plants synthesize metabolites belonging to diverse groups of compounds. These include triterpenoid saponins, flavonoids, phenolic acids, coumarins, volatile organic compounds, polyacetylenes, ecdysteroids, phytosterols, lignans, betaines, carotenoids, and anthraquinones. Some of the structures of these compounds are rare in the plant kingdom. The pharmacological potential of the Saniculeae species as antioxidant, anti-inflammatory, antimicrobial, antiviral, antiprotozoal, antitumor, antidiabetic, hypocholesterolemic, and neuroprotective agents has been explored in several studies. In addition, traditional medicinal uses have been discussed to provide a comprehensive picture of this subfamily. It is known that these plants have been used to treat dermatological diseases, respiratory issues, gastrointestinal problems, inflammations, wound healing, and cancers. As far as the author is aware, this is the first study conducted on this subfamily. Therefore, this review paper is the first to examine the little-known Saniculeae genera regarding their phytochemical and pharmacological characteristics. Studies showed that Saniculeae genera synthesize distinct secondary metabolites. Therefore, further research should be conducted on the exploration of these metabolites. The pharmacological investigation should also validate their potential efficacy in treating specific ailments and support their inclusion in modern healthcare practices.

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Amazonian Eryngium foetidum leaves exhibited very high contents of bioactive compounds and high singlet oxygen quenching capacity

Cited by 20 publications

References 40 publications

Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species

Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species

Eryngium foetidum L. (Apiaceae): A Literature Review of Traditional Uses, Chemical Composition, and Pharmacological Activities

Little-known Saniculeae genera: phytochemical studies and pharmaceutical activities

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