Amberlite IRA900N₃ as a New Catalyst for the Azidation of α,β‐Unsaturated Ketones under Solvent‐Free Conditions.

Abstract

Azide formation O 0272Amberlite IRA900N3 as a New Catalyst for the Azidation of α,β-Unsaturated Ketones under Solvent-Free Conditions. -The title catalyst is generated in situ and found to be highly efficient for the azidation of α,β-unsaturated ketones. It allows mild and environmentally friendly formation of a number of β-azido ketones which are versatile building blocks. -(CASTRICA, L.; FRINGUELLI*, F.; GREGOLI, L.; PIZZO, F.; VACCARO, L.; J. Org. Chem. 71 (2006) 25, 9536-9539; Dip. Chim., Univ. Perugia, I-06123 Perugia, Italy; Eng.) -Jannicke 15-034

Waste Minimized Multistep Preparation in Flow of β-Amino Acids Starting from α,β-Unsaturated Carboxylic Acids

“…In the past few years, we have reported the use of polystyrene-supported ammonium fluorides (Amberlite IRA900F, Amb-F and PS-DABCOF 2 ) as catalytic systems for the β-azidation of α,β-unsaturated ketones in water or under solvent-free conditions (SolFC). , …”