Ambient air plasma pre‐treatment of non‐woven fabrics for deposition of antibacterial poly (l‐lactide) nanoparticles

Abstract

Production of medical dressings specific to infected wounds remains one of the great challenges in medicine. In this paper, an integrated application that allows the immobilization of poly(L-lactide) (PLLA) nanoparticles (NPs) containing the antimicrobial agent octenidine on non-woven fabrics (NWs) is investigated. Nonthermal plasma generated by atmospheric pressure diffuse coplanar surface barrier discharge (DCSBD) was used for activation, modification, and improvement of the surface properties of polyethylene terephthalate (PET) and polypropylene (PP) NWs.The DCSBD system was integrated into a roll-to-roll production setup that prepared NWs for deposition of NPs using purpose-adapted inkjet printing equipment. The surface properties of the plasma-treated polymers were examined by means of strikethrough time (SST) measurements and X-ray photoelectron spectroscopy. The plasma modification of PET and PP NWs improved NP distribution and enabled uniform diffusion over polymer surfaces. The SST measurements indicate improvements in the hydrophilicity and permeability of plasma-treated PET and PP fabrics by reducing strike-through time from 400 s (for untreated polymers) to 6 s. This continuous method of delivering NPs onto plasma-pretreated polymer surfaces has the potential to be adapted to impregnated dressing production, with considerable benefits in terms of cheapness, convenience, speed, and full automation.atmospheric ambient air plasma, diffuse coplanar surface barrier discharge (DCSBD), non-woven polymer fabrics, poly(L-lactide)-octenidine nanoparticles, roll-to-roll plasma treatment

Biofunctionalization of Textile Materials.1. Biofunctionalization of Poly(Propylene) (PP) Nonwovens Fabrics by Alafosfalin

“…TT and fibrinogen concentration [15] PP-g-PLLA-Oct-HSA Active dressings for the treatment of wounds E. coli; S. aureus [16] PP-g-PLLA-Oct Medical dressings specific to infected wounds E. coli; S. aureus [17] AA-acrylic acid; Cg-collagen; Cs-chitosan; GMA-glycidyl methacrylate (GMA); HMG-Hexamethylenediamine guanidine hydrochloride; Gc-gentamycine chloride; g-grafted; H-heparin NIPAAm-N-isopropyl acrylamide; NVP-N-Vinyl-2-pyrrolidone; Oct-octenidine; PLLA-poly(L-lactide); PP-polypropylene nonwoven; aPTT-activated partial thromboplastin time.…”

Solar photocatalytic disinfection using ink-jet printed composite TiO2/SiO2 thin films on flexible substrate: Applicability to drinking and marine water

“…The DCSBD unit can generate high-power-density surface plasma (100 W/cm 3 ) at low temperature of 70 °C (Homola et al, 2016). The RPS400 for rollto-roll is compatible with state of the art roll-to-roll production and enables to quickly modify TiO2/SiO2 coatings on flexible substrates, without any damage to its bulk structure, which can find application in fast roll-to-roll manufacture (Ivanova et al, 2017.…”

Multi-Hollow Surface Dielectric Barrier Discharge for Bacterial Biofilm Decontamination

“…The hydroxyl (OH) radical belongs to the essential reactive agents applied for the generation of OH functional groups on the treated surface and hydrogen peroxide (H 2 O 2 ) in plasma products [ 1 , 2 ]. Such products can enhance biocompatibility and nanoparticle immobilization, and clean and decontaminate various surfaces [ 3 , 4 , 5 ]. Currently, the novel approaches using LTPs are studied to prepare self-cleaning, antibacterial, and biocompatible substrates, especially textiles with smart coatings [ 6 , 7 , 8 , 9 ].…”