2020
DOI: 10.1136/bmjresp-2020-000684
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Ambient air pollution, lung function and COPD: cross-sectional analysis from the WHO Study of AGEing and adult health wave 1

Abstract: BackgroundLong-term exposure to ambient air pollution leads to respiratory morbidity and mortality; however, the evidence of the effect on lung function and chronic obstructive pulmonary disease (COPD) in older adult populations is inconsistent.ObjectiveTo address this knowledge gap, we investigated the associations between particulate matter (PM), nitrogen dioxide (NO2) exposure and lung function, as well as COPD prevalence, in older Chinese adults.MethodsWe used data from the WHO Study on global AGEing and a… Show more

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Cited by 26 publications
(11 citation statements)
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References 38 publications
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“…Our study showed that subjects with abnormal lung functions were significantly older than those with normal lung functions. This finding indicates that older age and long-term exposure to air pollutants might be risk factors for lung diseases, particularly COPD, which is similar to findings of some other studies [48,49]. Moreover, our study also showed that abnormal lung functions were associated with breathlessness.…”
Section: Discussionsupporting
confidence: 92%
“…Our study showed that subjects with abnormal lung functions were significantly older than those with normal lung functions. This finding indicates that older age and long-term exposure to air pollutants might be risk factors for lung diseases, particularly COPD, which is similar to findings of some other studies [48,49]. Moreover, our study also showed that abnormal lung functions were associated with breathlessness.…”
Section: Discussionsupporting
confidence: 92%
“…Doiron et al, [41] Lin et al, [42] Adam et al, [11] and Ackermann-Liebrich et al [16] similarly described decline in FVC, FEV1, and FEV1/FVC due to chronic exposure to ambient air pollution. In contrast to the present study and other studies mentioned above, Elbarbary et al [43] found decline in FEV1 and FEV1/FVC but not in FVC due to chronic exposure to ambient air pollution.…”
Section: Fev1 Fvc and Fev1/fvccontrasting
confidence: 99%
“…In adults, high long-term exposure to ambient air pollution is also associated with a greater area of emphysema in computer tomography scans as well as lower FEV1 volumes during spirometry tests [ 31 ]. A similar effect was observed by Elbarbary et al, who reported that increases in PM 2.5 , PM 10 and NO 2 reduced FEV1 and FVC values [ 32 ].…”
Section: International Perspective On Air Pollutionsupporting
confidence: 83%