Ambulatory Labor Epidural Analgesia: Bupivacaine Versus Ropivacaine

Campbell, David; Zwack, Rhonda M.; Crone, Lesley-Ann; Yip, Ray

doi:10.1097/00000539-200006000-00023

Cited by 91 publications

(39 citation statements)

References 15 publications

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“…14 In a study utilizing 40 µg epidural fentanyl with 20 mL 0.08% bupivacaine, the analgesic duration was shown to be 91 ± 24 min. 15 These times are significantly less than the analgesia in our previous studies of epidural opioids, [1][2][3][4] as well as in the current study (135-145 min). However, Breen et al's study population included both primigravidous and multigravidous patients.…”

Section: Objectifcontrasting

confidence: 56%

The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour

Parker

Connelly

Lucas

et al. 2002

Can J Anesth/J Can Anesth

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Section: Objectifcontrasting

confidence: 56%

The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour

Parker

Connelly

Lucas

et al. 2002

Can J Anesth/J Can Anesth

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“…Fetocide was performed under patient-controlled epidural analgesia using ropicovaine (0.1%) and sufentanil (0.5 Ag/mL). This technique allowed for ambulatory analgesia during cervical maturation and first stage of labour 26,27 . The epidural level was adjusted if necessary to obtain a T8 level just before fetocide.…”

Section: Methodsmentioning

confidence: 99%

The use of lidocaine for fetocide in late termination of pregnancy

Senat¹

2003

BJOG: An International Journal of Obstetrics and Gynaecology

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“…In this study, 10% of patients in Group B and 6.7% in Group R had intrapartum urinary retention (patients catheterized with K-90 catheter). Campbell et al [13] observed that ropivacaine (0.08%)/fentanyl group did not experienced urinary retention but 35% patients of bupivacaine (0.08%)/ fentanyl group experienced urinary retention.…”

Section: International Journal Of Medical Science and Public Healthmentioning

confidence: 99%

“…In our study, no patients developed bradycardia or respiratory depression in either group. Campbell et al [13] observed that there was no incidence of hypotension in either group (bupivacaine (0.08%)/fentanyl vs. ropivacaine (0.08%)/ fentanyl) whereas Fernández-Guisasola et al [6] compared the 0.0625% bupivacaine with 0.1% ropivacaine with fentanyl as an epidural infusion and observed 2 patients in bupivacaine group and 1 patient in ropivacaine group required ephedrine for hypotension. In this study, there was no incidence of pruritus in either group.…”

Section: International Journal Of Medical Science and Public Healthmentioning

confidence: 99%

Compare the efficacy of ropivacaine and bupivacaine with fentanyl for epidural labor analgesia

Gajjar¹,

Patel²

2017

Int J Med Sci Public Health

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INTRODUCTIONLabor, as the process of childbirth, is a painful experience for most of the women. The McGill pain questionnaire ranks pain in the upper part of pain scale between cancer and amputation of digit. Sir John Snow first administered chloroform to Queen Victoria for the birth of eighth Background: Attempts have been made to reduce or eliminate the pain associated with labor since ancient time. Obstetrics analgesia reached a new phase with lumbar epidural analgesia. We carried out a randomized study to evaluate and compare the analgesic efficacy of ropivacaine and bupivacaine with fentanyl on mother, on fetus and on the course of labor. Objectives: The aim of the present study was to evaluate and compare the analgesic efficacy of ropivacaine (0.125%) and bupivacaine (0.125%) with fentanyl on mother, fetus and on the course of labor, incidence of instrumental delivery, and the rate of cesarean section. Materials and Methods: Study was conducted in 60 term, primi or second gravida parturients with active phase of labor, with cervical dilatation 3-5 cm, with single fetus, vertex presentation belonging to American Society of Anesthesiology (ASA) Class I or II. The patients were randomly divided into two groups. After negative test dose, loading dose of 10 ml of 0.125% ropivacaine in Group R and 0.125% of bupivacaine in Group B with 2.5 µg/ml fentanyl in both groups was given as an initial dose for analgesia. Top up dose with 5 ml of 0.125% of ropivacaine in Group R and 0.125% bupivacaine in Group B were given when visual analog scale (VAS ≥3). For the second stage of labor 8 ml of 0.125% of ropivacaine in Group R and 0.125% of bupivacaine in Group B with 1.25 µg/ml fentanyl in both groups were given in sitting position to allow perineal analgesia. Results: In this study, we observed that maximum number of patients have developed sensory block up to T8, 50% in Group B and 53.3% in Group R, only 2 patients (6.7%) in Group B developed T6 level, and no patients in Group R. There was no significant difference in mean total dose of bupivacaine and ropivacaine (P > 0.05). In Group R total 22 patients and 3 in Group B developed Grade 0 motor blocked, which was statistically very significant. In Group B, 14 and 2 patients developed Grade 2 and Grade 3 motor blocked, respectively, compared to none of the patients in Group R which was statistically very significant. There was no significant difference in Apgar score and VAS scores between the groups at any time during the first and second stage of labor. Conclusions: Ropivacaine group patients required less number of top-up doses and developed significantly less motor block than bupivacaine group patients. We thus conclude that the combinations of 0.125% of ropivacaine with fentanyl and 0.125% bupivacaine with fentanyl is equally effective in producing excellent labor analgesia ensuring the safety of the mother and fetus.

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Ambulatory Labor Epidural Analgesia: Bupivacaine Versus Ropivacaine

Cited by 91 publications

References 15 publications

The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour

The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour

The use of lidocaine for fetocide in late termination of pregnancy

Compare the efficacy of ropivacaine and bupivacaine with fentanyl for epidural labor analgesia

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