Amebic cerebral abscess mimicking bacterial meningitis

Emil, S. Sayhan; Altinel, Deniz; Bayol, Ümit; Ozcolpan, O.O.; Tan, Ayça; Ganiüsmen, Ozan

doi:10.1007/s12098-008-0182-7

Cited by 7 publications

(5 citation statements)

References 10 publications

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“…A clinical case of a 31-year-old man in Thailand describes an amebic abscess located in the right occipital lobe, concomitantly with acute supurative meningitis (Viriyavejakul and Riganti 2009). In the USA, a case was reported of a 2-year-old girl who had multiple brain abscesses in the right cerebral peduncle and in both hemispheres, with abundant inflammatory infiltrate, which came to be confused with bacterial meningitis (Sayhan Emil et al 2008). Based on these data and our results, we suggest that E. histolytica possibly shares membrane antigens and therefore some pathogenic mechanisms with N. fowleri.…”

Section: Resultssupporting

confidence: 69%

“…Because cerebral infections by bacteria have a medical profile similar to that of protozoans (including headaches, partial muscular weakness, lethargy, and dizziness), diagnosis is often difficult (Sayhan Emil et al 2008;Peralta-Rodriguez and Ayala-Oviedo 2009). Nevertheless, computerized axial tomography (CAT scans) and nuclear magnetic resonance (MRI) both provide data that can lead to the detection of this malady in 100% of the cases.…”

Section: Introductionmentioning

confidence: 99%

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Clinical case of cerebral amebiasis caused by E. histolytica

et al. 2011

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Although amebic brain abscess is a rare form of invasive amebiasis, when present, it is frequently lethal. This disorder always begins with the infection of the colon by Entamoeba histolytica trophozoites, which then travel to extra-intestinal tissues through the bloodstream. Amebic brain abscesses are produced when trophozoites invade the central nervous system. Computerized axial tomography scans can be used to diagnose the presence or absence of a brain abscess with a certainty of 100%. However, this diagnostic tool does not reveal the etiological agent of disease. By analyzing the clinical case of a patient that died due to untimely treatment of this malady, the present study aims to identify a diagnostic tool that can give a precise determination of the etiological agent and therefore permit adequate and opportune treatment. Currently, diagnosis of amebic brain abscess is often done by identification of the ameba in a biopsy or autopsy. By immunohistochemistry and immunofluorescence with specific antibodies, we identified the existence of E. histolytica, which presents proteins similar to Naegleria fowleri in its membrane.

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Section: Resultssupporting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Clinical case of cerebral amebiasis caused by E. histolytica

et al. 2011

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“…[26] Other group of patients at risk of unusual pathogens are the immigrants from underdeveloped countries, they can have, in addition to those pathogens affecting inmunocompromised patients, other pathogens like Taenia, E. histolytica, Schistosoma, Echinococcus, and Paragonimus. [26,[65][66][67][68][69][70][71] In the Nathoo et al [4] series (the biggest reported), it was found that majority of patients undergoing surgery (53.2%) had isolation of a single organism, being the commonest the gram-positive organisms: S. aureus and Staphylococcus epidermidis, especially in traumatic BA. Streptococcus milleri isolates were predominant in patients with paranasal sinusitis, whereas Proteus mirabilis was most commonly isolated in otogenic infections.…”

Section: Etiologymentioning

confidence: 99%

Brain abscess: Current management

Alvis-Miranda

Castellar-Leones

Elzain³

et al. 2013

Journal of Neurosciences in Rural Practice

138

137

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Brain abscess (BA) is defined as a focal infection within the brain parenchyma, which starts as a localized area of cerebritis, which is subsequently converted into a collection of pus within a well-vascularized capsule. BA must be differentiated from parameningeal infections, including epidural abscess and subdural empyema. The BA is a challenge for the neurosurgeon because it is needed good clinical, pharmacological, and surgical skills for providing good clinical outcomes and prognosis to BA patients. Considered an infrequent brain infection, BA could be a devastator entity that easily left the patient into dead. The aim of this work is to review the current concepts regarding epidemiology, pathophysiology, etiology, clinical presentation, diagnosis, and management of BA.

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“…Surgical intervention may be in the form of pus drainage or total excision of the abscess wall and is indicated in cases of a large, multiloculated abscess, no response to antibiotics, mass effect, poor Glasgow Coma Scale score, and development of new abscesses. [11,13,14,15] But our patient succumbed to the fuminant infection before the drugs could be administered.…”

Section: Discussionmentioning

confidence: 94%

Amoebic Cerebral Abscess: Still A Diagnostic Dilemma with Fatal Outcome

Jindal

Tyagi

Garg

et al. 2019

APALM

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Amoebiasis is defined as infection with Entamoeba histolytica, which enters the body through feco -oral route after consumption of food or water contaminated by cysts. We present a rare case of amoebic brain abscess in a 45 years old patient who came with headache, fever and right sided weakness for 15 days. He was emperically being treated for tuberculosis. As Entamoeba was not suspected, no serological or microbiological investigations for the same were done. Histopathological examination of abscess sent after frontal lobectomy revealed trophozoites of Entamoeba histolytica. Demonstration of trophozoites of Entamoeba on histopathology sections was a surprising finding which clinched the diagnosis in this case. Amoebic brain abscess should be considered as differential diagnosis in all patients who present with signs & symptoms of central nervous system involvement in endemic areas. Early diagnosis and aggressive management with metronidazole is imperative to limit the morbidity and prevent the mortality.

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Amebic cerebral abscess mimicking bacterial meningitis

Cited by 7 publications

References 10 publications

Clinical case of cerebral amebiasis caused by E. histolytica

Clinical case of cerebral amebiasis caused by E. histolytica

Brain abscess: Current management

Amoebic Cerebral Abscess: Still A Diagnostic Dilemma with Fatal Outcome

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