Amebic Liver Abscess

Hughes, Molly A.; Petri, William A.

doi:10.1016/s0891-5520(05)70121-5

Cited by 141 publications

(115 citation statements)

References 67 publications

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“…19 -22 In our study, 74.6% of the abscesses were located in the right lobe of liver, similar to previous studies and 87.3% of our patients had solitary abscesses, little more than what has been reported in other studies, similarly we encountered multiple liver abscesses in 12.69% of the patients, in contrast to similar to the 20-25% incidence of multiple liver abscesses reported by Sharma et al 16,19,21,23,24 In the present study we found 52.3% of the abscesses to be amoebic in etiology, 14.28% to be pyogenic, 133.3% to be indeterminate Khan et al in their series reported 68% amoebic, 21% pyogenic, 8% indeterminate, and 3% MLA. 25 The indeterminate abscess formed larger percentage in the present study probably due to the reasons that the patients might have taken antibiotics/antiamebics before reporting to the referral centre like ours.…”

Section: Discussionsupporting

confidence: 90%

Outcome of ultrasound guided pigtail catheter drainage of liver abscesses a prospective study of 126 cases

2015

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Background: With the advances in the intervention radiological techniques the laparotomy for liver abscess has been taken over by the percutaneous ultrasound guided needle aspiration as well as percutaneous ultrasound guided pigtail catheter drainage. This study was undertaken at Govt. Medical College & Associated hospitals, Jammu to assess the outcome of this minimally invasive procedure for Liver abscess. Methods: 126 patients were subjected to pigtail catheter drainage after localization with ultrasonography using modified Seldinger's technique. The pigtail catheters of 8-14 Fr size was were used. All the samples of pus were subjected to microscopy for EH trophozoites, Gram stain and for pus culture and sensitivity. Patient's vitals were monitored for 24 hours. Daily estimation of volume, colour and consistency of the drainage fluid was recorded. Follow-up USG was done on average of 5th postoperative day to assess the shrinkage of cavity and the amount of residual fluid. Removal of catheter was decided based on; the amount of pus drained (<50 ml for three consecutive days); disappearance of symptoms & signs; and USG abdomen showing signs of resolution. Results: The age of the patients in this study ranged from the 21 years to 70 years with M: F ratio of 13.5: 1. Pain, fever, tender hepatomegaly & anaemia were common symptomatology. Right lobe abscess was seen in 74.60% (n=94) of patients. Solitary abscess was seen in 110 patients (87.3%). 66 patients (52.38%) had ALA, 18 patients PLA & 42 were having indeterminate liver abscess. Smaller size catheter specially 8-10 Fr invariably blocks. Common problems encountered were local pain or discomfort due to catheter, peri-tubal leak in few cases, and local wound infection. The average period of continuous catheter drainage was 7.2 days maximum being 26 days. Average duration of hospital stay was 2.45 days. Success rate of the procedure was 96.82% (n=122). 04 patients needed laparotomy. Conclusions: Advances in interventional radiology have influenced management of liver abscess. We in our series of 126 pts of liver abscess conclude that image guided percutaneous pigtail drainage of liver abscess is a safe, effective minimally invasive procedure with negligible morbidity and no mortality. High procedural success rate has almost replaced conventional laparotomy in uncomplicated liver abscess.

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Section: Discussionsupporting

confidence: 90%

Outcome of ultrasound guided pigtail catheter drainage of liver abscesses a prospective study of 126 cases

2015

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“…2,4-6 These two symptoms were also the most common clinical manifestations based on a review of the literature, 1,7,10,16,17 even for those patients with moderate or severe disease. These symptoms were also common for HIV-and non-HIV-infected groups.…”

Section: Discussionmentioning

confidence: 98%

Clinical Manifestations and Risk Factors of Amebic Liver Abscess in Southeast Taiwan Compared with Other Regions of Taiwan

Chen

Bair

Lin

et al. 2013

The American Society of Tropical Medicine and Hygiene

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Abstract. Amebic liver abscess (ALA) had previously been endemic in Taiwan, particularly in the southern region, although its occurrence in the southeastern area was unknown. Thus, we conducted a retrospective study for southeastern Taiwan. We identified 14 patients who were diagnosed with ALA between July of 1995 and July of 2008. These patients were predominantly male and older in age. Most patients lived in rural areas (85.7%). Alcoholism (78.6%) and diabetes (35.7%) were risk factors for ALA. No human immunodeficiency virus (HIV) infections were detected. The most common clinical symptoms were fever (100%) and abdominal pain (100%). Short mean durations of symptoms, high bilirubin levels, and low albumin levels were also noted. Most patients (92.86%) had a single lesion, particularly in the right liver lobe (71.4%). Six patients also had secondary Klebsiella pneumoniae bacterial infections. Clinicians should be aware of the different risk factors in different regions when diagnosing amebic liver abscess in Taiwan.

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“…The spectrum of diseases caused by this parasite includes intestinal infection (amoebic colitis), as well as extra-intestinal infection, mostly in the form of amoebic liver abscess (ALA) (2). Various factors like poor hygiene (3), diabetes (4), or steroid-overuse (5) have been knownto predispose to the development of ALA.…”

Section: Introductionmentioning

confidence: 99%

Alcohol Consumption, Hepatic Iron Load and the Risk of Amoebic Liver Abscess: A Case-control Study

2003

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Objective It is unknown why most amoebic liver abscess (ALA) cases occur in alcohol drinkers. In experimental studies, the presence of 'iron' potentiates the invitro growth of Entamoeba histolytica (E. histolytica), and is also known to increase its in-vivo invasiveness in animal infections. Chronic alcoholism increases the hepatic iron deposition. Wehypothesized that ALAoccurs more commonlyin livers with a high iron load as in alcoholics.To test this hypothesis we compared the levels of iron between ALAand non-ALA cases belonging to alcoholic and non-alcoholic groups. Methods Out of a total of 48 ALAcases, 34 (70%) were alcoholics and 14 (30%) were non-alcoholics. After applying exclusion criteria, serum iron and liver iron stores were quantified in 20 ALAcases (10 alcoholic and 10 non-alcoholics) and compared with 20 non-ALA cases (10 alcoholics and 10 non-alcoholics).Results All patients of ALAhad serum iron values within the normal range but higher than non-ALAcases. In the liver tissue, most patients with ALAhad higher (grade II or III) iron deposition, than non-ALAcases (mostly grade I). Thus, patients with ALA, with or without alcohol indulgence, had higher iron levels when compared to the non-ALA cases.Conclusion It appears that the higher incidence of ALA in alcoholic livers is possibly due to their higher iron content. (Internal Medicine 42: 644-649, 2003)

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Amebic Liver Abscess

Cited by 141 publications

References 67 publications

Outcome of ultrasound guided pigtail catheter drainage of liver abscesses a prospective study of 126 cases

Outcome of ultrasound guided pigtail catheter drainage of liver abscesses a prospective study of 126 cases

Clinical Manifestations and Risk Factors of Amebic Liver Abscess in Southeast Taiwan Compared with Other Regions of Taiwan

Alcohol Consumption, Hepatic Iron Load and the Risk of Amoebic Liver Abscess: A Case-control Study

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