Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer

Fernandes, Hilda; D'Souza, Clement R. S.; Swethadri, Gumballi Krishnamurthy; Naik, Chamarajanagar Nanjanayak Ramesh

doi:10.4103/0377-4929.48927

Cited by 25 publications

(21 citation statements)

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“…The findings on imaging, mentioned earlier, were strongly suggestive of a metastatic colonic malignancy. Similar cases have been reported earlier [5,8] thereby reiterating that a colonic amoeboma accompanied by amoebic liver abscess may be misdiagnosed as a metastatic colonic malignancy. A high index of suspicion is thus essential when dealing with colonic masses and liver lesions, especially in the tropics.…”

Section: Discussionsupporting

confidence: 55%

Amoeboma—Lest We Forget!!!

2015

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Amoebiasis is an infection with the parasitic intestinal protozoan Entamoeba histolytica (E. histolytica). Most infections are usually asymptomatic, but the disease spectrum can range from dysentery to extraintestinal infections, including liver abscesses. The management of a 68-year-old male with amoeboma, a rare manifestation of intestinal amoebiasis, is described along with a review of literature.

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Section: Discussionsupporting

confidence: 55%

Amoeboma—Lest We Forget!!!

2015

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“…[9] and Farnandes et al . [10] also found cases of amoebic colitis that caused diagnostic uncertainty by mimicking a colonic carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Amoeboma of colon mimicking colonic carcinoma

et al. 2014

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Entamoeba histolytica is a major cause of diarrhea in the developing countries and it can present with a wide range of gastrointestinal symptoms depending on the phase of the infection. We describe a case of 65-year-old male patient presented with abdominal pain and vomiting. On the clinical and radiological examination provisional diagnosis of colonic carcinoma was suspected. After resection of perforated caecal growth, histopathological sections showed numerous trophozoites of E. histolytica in a background of abundant necrosis. This case revealed differentiation between amoeboma and carcinoma is critical.

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“…In the present case it was not suspected by imaging studies and because presentation was without jaundice although lesion infiltrate Vater ampulla, making more difficult to suspect, with surgical remotion by Whipple procedure but without a consensus on management by the rarity of the case. Differential diagnosis includes ileocecal tumor like tuberculoma, lymphoma, adenocarcinoma, Crohn disease, atypical fungal disease, arterialvenous malformations and diverticulitis [9,10]. Histologically it could be observed flask look like ulcers extending to submucosa layer, associated with a necrotic and inflammatory extensive exudate.…”

Section: Discussionmentioning

confidence: 99%

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2016

MOJCR

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Aim: An inflammatory and proliferative response to amibiasis infection is known as ameboma, a pseudotumoral lesion; the ascendant colon is the most frequent location.Case report: A male of 65 years-old referring diarrhea and epigastric pain comes to emergency room. At physical exam with tachycardia, tachypnea, abdominal pain located in epigastrium, right iliac fossae and rebound sign. Laboratories report leukocytosis, neutrophilia and eosinophilia. Abdominal ultrasound reports a paracecal abscess, probably secondary to acute appendicitis. Laparotomy was performed finding an infiltrating tumoral lesion in ascendant colon, with perforation and abscess extended to the duodenum, and another tumoral lesion in Vater ampulla. A right extended hemicolectomy was performed with oncological approach and, after 48 hours in the Intensive Care Unit, Whipple procedure was completed. Patient developed amebic colitis with sigmoidal perforation and a subtotal colectomy was completed. After medical treatment, patient presents multiple organic failure and died at 9th day. Histopathological exam reports Vater ampulla ameboma with extension to pancreas, right colon ameboma, and ulcerative amibiasis in colon. Conclusion:At our knowledge this is the first reported case of Vater ampulla ameboma in literature. The diagnosis of this lesions are difficult inclusive after CT scan, but it can be treated medically. It must be considered in the differential diagnosis of colonic tumors and, in case of suspect in an acute abdomen scenario, the source must be treated and resection avoided if possible.

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Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer

Cited by 25 publications

References 0 publications

Amoeboma—Lest We Forget!!!

Amoeboma—Lest We Forget!!!

Amoeboma of colon mimicking colonic carcinoma

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