Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted

So, Noah L W; Chan, C F; Ho, Kenneth Wai Yip; Lam, Yuk-Fai

doi:10.12809/hkmj133987

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…[ 4 6 ] Notably, the case under study also presented as a pyogenic granuloma. Various morphological presentations of AMM have been reported in the literature, which include erythematous patch, plaque, nonpigmented papule, red nodule, ulcerated nodule, and paronychia[ 3 7 8 9 10 11 ] [ Table 1 ]. Similarly, the index case also presented as erythematous nodule.…”

Section: Discussionmentioning

confidence: 99%

Amelanotic melanoma in the vicinity of acquired melanocytic nevi and not arising from agminated melanocytic nevi: Masquerading as pyogenic granuloma

et al. 2016

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Amelanotic melanoma (AMM) presenting as pyogenic granuloma and occurring in the vicinity of acquired melanocytic nevi is rare. Herein, we report such a manifestation in a 68-year-old male who presented with the painful red nodule and multiple pigmented patches involving the left great toe. Histopathological examination of skin biopsy taken from the nodule with an immunohistochemical study using HMB45 and S-100 confirmed the diagnosis of AMM. Biopsy from the pigmented patch near the nodule showed features of melanocytic nevus. Investigative work up revealed metastatic deposits in the left inguinal lymph node with no evidence of systemic involvement, placing him in malignant melanoma Stage IIIC of American Joint Committee on Cancer (AJCC) tumor node metastasis system. The development of AMM in the vicinity of acquired melanocytic nevi and manifesting as granuloma pyogenicum is unique in this case.

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Section: Discussionmentioning

confidence: 99%

Amelanotic melanoma in the vicinity of acquired melanocytic nevi and not arising from agminated melanocytic nevi: Masquerading as pyogenic granuloma

et al. 2016

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Lesión dolorosa plantar. Diagnóstico y comentario

Rebull

Ortíz

Masi

2016

Piel

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Clinical and dermoscopic features of truly amelanotic plantar melanoma

Giorgi

Gori²,

Savarese

et al. 2017

Melanoma Research

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Currently, there are no specific clinical and dermoscopic features for diagnosing truly amelanotic plantar melanoma (TAPM). The present study aimed to investigate the dermoscopic features of all clinical variants of TAMPS and to evaluate their histopathological correlations. A retrospective analysis of prospectively collected data was carried out during a 10-year period (2003-2013). We analyzed the clinical data of 1321 patients, who had received a histological diagnosis of melanoma at the Melanoma Unit of the University of Florence. We selected the clinical and dermoscopic images of TAPMs and analyzed the presence of dermoscopic parameters. Incorrect preoperative diagnoses were analyzed to highlight peculiar dermoscopic features of pinkish plantar melanomas, the clinical diagnosis of which is extremely challenging for the dermatologist. Of all 1321 patients, 29 (24%) had TAPMs. Importantly, only 20.7% of patients with TAPMs had a correct preoperative diagnosis of suspicious melanocytic lesion. On the basis of the initial misdiagnosis, TAPMs were categorized as eczema-like, verruca-like, angioma-like lesions. Dermoscopically, all TAPMs showed the presence of a well-defined 'erythematous homogeneous area' with an atypical polymorphous vascular pattern with dotted, globular, and glomerular vessels. Our study highlights a crucial dermoscopic feature of TAPMs, the 'erythematous homogeneous area' that is characteristic of the plantar region, and, to our knowledge and experience, has not been described in nonacral amelanotic melanomas.

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Amelanotic melanoma masquerading as a pyogenic granuloma: caution warranted

Cited by 4 publications

References 2 publications

Amelanotic melanoma in the vicinity of acquired melanocytic nevi and not arising from agminated melanocytic nevi: Masquerading as pyogenic granuloma

Amelanotic melanoma in the vicinity of acquired melanocytic nevi and not arising from agminated melanocytic nevi: Masquerading as pyogenic granuloma

Lesión dolorosa plantar. Diagnóstico y comentario

Clinical and dermoscopic features of truly amelanotic plantar melanoma

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