Ameliorating effects of goby fish protein hydrolysates on high-fat-high-fructose diet-induced hyperglycemia, oxidative stress and deterioration of kidney function in rats

Nasri, Rim; Abdelhedi, Ola; Jemil, Ines; Daoued, Ines; Hamden, Khaled; Kallel, Choumous; Elfeki, Abdelfattah; Lamri‐Senhadji, Myriem; Boualga, Ahmed; Nasri, Monçef; Karra-Châabouni, Maha

doi:10.1016/j.cbi.2015.08.003

Cited by 67 publications

(48 citation statements)

References 40 publications

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“…However, administration of USP to HCD-fed rats didn't decrease the level of a-amylase activity. These findings are in agreement with those of Nasri et al (2015) who reported that goby protein hydrolysates and not undigested goby proteins were found to decrease a-amylase activity. The obtained results proved that administration of FSPHs could protect rats against hyperglycemia induced by hypercaloric diet.…”

Section: Effect Of Fsphs On A-amylase Activity In Plasmasupporting

confidence: 93%

“…In another study, Nasri et al (2015) have shown the preventive role of goby protein hydrolysates against kidney deterioration and uric acid hyperfiltration.…”

Section: Effect Of Usp and Fsphs On Kidney Functionmentioning

confidence: 93%

“…In a recent study, Nasri et al (2015) reported the hypoglycemic effects of protein hydrolysates from goby on high-fat-high-fructose diet-fed rats.…”

Section: Effects Of Fsphs On Blood Glucose Levelsmentioning

confidence: 99%

“…Although several protein hydrolysates have been produced by enzymatic hydrolysis Nasri et al 2015), few studies have been conducted on the generation of biologically active peptides using microbial fermentation. In our previous study, we reported the production of protein hydrolysates from different fish species prepared by fermentation with Bacillus subtilis A26, exhibiting antioxidant activities (Jemil et al 2014).…”

Section: Introductionmentioning

confidence: 99%

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Beneficial effects of fermented sardinelle protein hydrolysates on hypercaloric diet induced hyperglycemia, oxidative stress and deterioration of kidney function in wistar rats

et al. 2017

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This study investigated the potential effects of fermented sardinelle protein hydrolysates (FSPHs) obtained by two proteolytic bacteria, Bacillus subtilis A26 (FSPH-A26) and Bacillus amyloliquefaciens An6 (FSPHAn6), on hypercaloric diet (HCD) induced hyperglycemia and oxidative stress in rats. Effects of FSPHs on blood glucose level, glucose tolerance, a-amylase activity and hepatic glycogen content were investigated, as well as their effect on the oxidative stress state. Biochemical findings revealed that, while undigested sardinelle proteins did not exhibit hypoglycemic activity, oral administration of FSPHs to HCD-fed rats reduced significantly a-amylase activity as well as glycemia and hepatic glycogen levels. Further, the treatment with FSPHs improved the redox status by decreasing the levels of lipid peroxidation products and increasing the activities of the antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase) and the level of glutathione in the liver and kidneys, as compared to those of HCD-fed rats. FSPHs were also found to exert significant protective effects on liver and kidney functions, evidenced by a marked decrease in alkaline phosphatase activity and a modulation of creatinine and uric acid contents. These results indicated the beneficial effect of FSPHs on the prevention from hyperglycemia and oxidative stress.

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Section: Effect Of Fsphs On A-amylase Activity In Plasmasupporting

confidence: 93%

“…In another study, Nasri et al (2015) have shown the preventive role of goby protein hydrolysates against kidney deterioration and uric acid hyperfiltration.…”

Section: Effect Of Usp and Fsphs On Kidney Functionmentioning

confidence: 93%

“…In a recent study, Nasri et al (2015) reported the hypoglycemic effects of protein hydrolysates from goby on high-fat-high-fructose diet-fed rats.…”

Section: Effects Of Fsphs On Blood Glucose Levelsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Beneficial effects of fermented sardinelle protein hydrolysates on hypercaloric diet induced hyperglycemia, oxidative stress and deterioration of kidney function in wistar rats

et al. 2017

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“…10 Following a study about the effects of cereal-mix fermented with probiotic on high cholesterol fed rats; Ogunremi et al, 31 showed that cereal-based functional food positively inuenced serum lipid levels but clearly increased the plasma glucose level. In fact, signicant increases in the plasma glucose content were recorded with an increasing supplementation of Table 6 Effect of experimental diets on some kidney function parameters in different rat groups a Control: normal rats; Chol: rats which were fed a cholesterol-rich diet for 1 month; Und: hypercholesterolemic rats given undigested muscle for 1 month; MH: hypercholesterolemic rats given muscle hydrolysate for 1 month.…”

Section: Evaluation Of Hypoglycemic Effectsmentioning

confidence: 99%

Protective effects of thornback ray muscle protein hydrolysate against dyslipidemia, oxidative stress and reduced fertility induced by high cholesterol diet in adult male rats

et al. 2018

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a Enzymatic thornback ray (Raja clavata) muscle hydrolysates have been shown to have antioxidant and antihypertensive activities in vitro. The Neutrase hydrolysate exhibited the highest activities, so it was investigated along with the undigested muscle to test their hypolipidemic, antioxidative and fertility effects in rats fed with a high-cholesterol diet (HCD). Animals were allocated into four groups of 5 rats each: a normal diet group (control), a HCD group, and two groups of HCD with a daily dose of undigested muscle (Und) or the hydrolysate (MH) at 0.7 g kg À1 of body weight. All animals received their respective treatments daily for 1 month. After the treatment period, serum lipid profiles, the activities of alanine aminotransferase and aspartate aminotransferase, the level of malonaldehyde, the activities of antioxidant enzymes (catalase and glutathione peroxidase) in the liver and sperm fertility parameters (in the epididymis and testis) were determined. Compared with those fed a standard diet, HCD induced dyslipidemia and oxidative stress, and decreased numerous reproductive parameters (mobility, count and viability). Interestingly, supplementing the HCD with thornback ray proteins attenuated all these anomalies, especially in the case where they were hydrolysed. These observations suggested that these proteins might contain bioactive peptides that possess hypocholesterolemic and antioxidant activities that ameliorate sperm damage.

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Bioactive Peptides from Fish Collagen Byproducts

Nasri

2019

Byproducts From Agriculture and Fisheries

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Ameliorating effects of goby fish protein hydrolysates on high-fat-high-fructose diet-induced hyperglycemia, oxidative stress and deterioration of kidney function in rats

Cited by 67 publications

References 40 publications

Beneficial effects of fermented sardinelle protein hydrolysates on hypercaloric diet induced hyperglycemia, oxidative stress and deterioration of kidney function in wistar rats

Beneficial effects of fermented sardinelle protein hydrolysates on hypercaloric diet induced hyperglycemia, oxidative stress and deterioration of kidney function in wistar rats

Protective effects of thornback ray muscle protein hydrolysate against dyslipidemia, oxidative stress and reduced fertility induced by high cholesterol diet in adult male rats

Bioactive Peptides from Fish Collagen Byproducts

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