2018
DOI: 10.9734/jabb/2018/43249
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Ameliorating Potential of Honey on Caffeine Induced Sperm Toxicity in Male Albino Rats

Abstract: This study evaluated the ameliorating effect of honey on caffeine-induced sperm toxicity in male albino rats. Thirty healthy male albino rats of 12 weeks old were divided into five groups with six rats in each group using a Completely Randomized Design (CRD). The experimental animals were treated with combinations of caffeine and honey orally. Group 1 served as the control and was given only water and feed; Group 2 (honey group) received 10 ml/kgBW of honey; Group 3 (caffeine group) received 200 mg/kgBW of caf… Show more

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Cited by 2 publications
(2 citation statements)
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“…Phyllanthus amarus extracts are locally used as anti-inflammatory analgesics [9,10], pointing that it may induce mutations on sperm cells during spermatogenic processes; though it may be administered as an analgesics, anti-malaria drug or for other purposes. Sperm head abnormalities in animals treated with caffeine was documented by Ekaluo et al [37] and Uno et al [38][39] also disclosing induced mutation on sperm cells during spermatogenic processes, resulting in sperm head abnormalities. These reports are similar to our present findings on sperm head abnormalities due to disruption during spermatogenesis.…”
Section: Discussionmentioning
confidence: 96%
“…Phyllanthus amarus extracts are locally used as anti-inflammatory analgesics [9,10], pointing that it may induce mutations on sperm cells during spermatogenic processes; though it may be administered as an analgesics, anti-malaria drug or for other purposes. Sperm head abnormalities in animals treated with caffeine was documented by Ekaluo et al [37] and Uno et al [38][39] also disclosing induced mutation on sperm cells during spermatogenic processes, resulting in sperm head abnormalities. These reports are similar to our present findings on sperm head abnormalities due to disruption during spermatogenesis.…”
Section: Discussionmentioning
confidence: 96%
“…Furthermore, Acanthopanacis senticosi activates sperm motility when administrated in humans ( 34 ). Moreover, Sesamum indicum , administrated at 0.5 mg/kg during 3 months, improves sperm count, motility and normal morphology ( 35 , 36 ). In addition, roots of Withania somnifera administrated 5 g/day during 3 months improve energy metabolism and quality of semen and reproductive hormone levels in infertile men ( 37 ).…”
Section: Treatment For Male Infertilitymentioning
confidence: 99%