Amelioration of pulmonary aflatoxicosis by green tea extract: An in vivo study

Mostafa, Heba El-Sayed; Allithy, Amal Nooredeen Ahmed; Abdellatif, Nassar Ayoub; Anani, Maha; Fareed, Shimaa Antar; El-Shafei, Dalia Abdallah; El-Din, Eman Ahmed Alaa

doi:10.1016/j.toxicon.2020.11.009

Cited by 9 publications

(1 citation statement)

References 47 publications

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“…Reproductive toxicity of AFB 1 has been demonstrated in vivo on mice [110]. Pulmonary toxicity of AFB 1 has been observed in vivo on male albino rats [117]. Gastrointestinal toxicity of AFB 1 has been described in vivo on rats [118], pigs [119], and chickens [120].…”

Section: Recent Data On Aflatoxin Toxicitymentioning

confidence: 99%

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Pickova

Ostrý

Toman

et al. 2021

Toxins

111

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In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults died by hitherto unknown turkey “X” disease in England. The disease was associated with Brazilian groundnut meal affected by Aspergillus flavus. The toxin was named Aspergillus flavus toxin—aflatoxin. From the point of view of agriculture, aflatoxins show the utmost importance. Until now, a total of 20 aflatoxins have been described, with B1, B2, G1, and G2 aflatoxins being the most significant. Contamination by aflatoxins is a global health problem. Aflatoxins pose acutely toxic, teratogenic, immunosuppressive, carcinogenic, and teratogenic effects. Besides food insecurity and human health, aflatoxins affect humanity at different levels, such as social, economical, and political. Great emphasis is placed on aflatoxin mitigation using biocontrol methods. Thus, this review is focused on aflatoxins in terms of historical development, the principal milestones of aflatoxin research, and recent data on their toxicity and different ways of mitigation.

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