Ameliorative effect of Nigella sativa conjugated silver nanoparticles against chromium-induced hepatotoxicity and renal toxicity in mice

Nauroze, Tooba; Ali, Shaukat; Kanwal, Lubna; Ara, Chaman; Mughal, Tufail Akbar; Andleeb, Shagufta

doi:10.1016/j.sjbs.2023.103571

Cited by 10 publications

(4 citation statements)

References 61 publications

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“…The biosynthesis of AgNPs was conducted according to the procedure outlined in our earlier research, [21][22][23] with slight modifications. Diverse parameters, such as reactant concentration, ratio, pH levels, and incubation time, were thoroughly adjusted by changing one factor at a time while keeping constant values for the other variables.…”

Section: Biosynthesis Of Blr-agnpsmentioning

confidence: 99%

“…Total trials were conducted in compliance with international laws and adhered to the ethical guidelines set forth by the University for the humane treatment of experimental animals, as outlined in our prior research. [18][19][20][21][22][23][25][26][27] The Ethics Committee of the Faculty of Science at GC University, Lahore, Pakistan, granted ethical approval for this study under approval number GCU-IIB 118.…”

Section: Ethical Statementmentioning

confidence: 99%

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Antibacterial and Wound Healing Efficacy of Silver Nanoparticles Synthesized from Root Bark ofBerberis lyciumRoyle

Mughal,

Ali,

Mumtaz

et al. 2024

ChemistrySelect

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Infectious diseases are becoming a worldwide threat due to antibiotic resistance. Therefore, it is necessary to prepare innovative antibiotics against bactericidal activities. The development of nanomedicine has been greatly aided by nanotechnology. A focal point of exploration involves the production of noble metal nanoparticles, owing to their diverse applications. The study's subjects are the synthesis, characterization, and assessment of silver nanoparticles (AgNPs) derived from Berberis lyceum Royle root bark (BLR) extract. The study revealed the potent antibacterial properties of BLR‐AgNPs, with heightened efficacy against S. pyogenes (16.7±0.3 mm) and comparatively lower activity against E. coli (1.1±0.1 mm). Minimum inhibitory concentration assessment indicated maximum activity at 10 μg/mL, whereas 2.5 μg/mL demonstrated the least inhibitory effect. Furthermore, the wound healing potential of BLR‐AgNPs was explored, demonstrating superior activity (0.19±0.02 cm) equated to BLR‐extract (0.46±0.02 cm) and untreated wounds (0.77±0.02 cm). These findings underscore the considerable antibacterial and wound‐healing capabilities of BLR‐AgNPs.

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Section: Biosynthesis Of Blr-agnpsmentioning

confidence: 99%

Section: Ethical Statementmentioning

confidence: 99%

Antibacterial and Wound Healing Efficacy of Silver Nanoparticles Synthesized from Root Bark ofBerberis lyciumRoyle

Mughal,

Ali,

Mumtaz

et al. 2024

ChemistrySelect

Self Cite

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“…The discharged Ag+ can destroy DNA, disrupt cell walls, and derangement of membrane proteins. These findings suggest that Ag sulfidation, which lowers Ag+ release and lessens Ag nanoparticle effects on gut microbiota, arises from Ag nanoparticle aging in food (Nauroze et al, 2023). Different other questions regarding the impact of silver-based nanoparticles still need to be debated.…”

Section: Silver-based Nanoparticlesmentioning

confidence: 99%

Use of Nanoparticles as Antioxidant Agents to Combat Bacterial Infections and its Benefits to Intestinal Microbiota and Immune Response

Khan,

Wei,

Fatima

et al. 2023

Complementary and Alternative Medicine: One Health Perspective

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“…Chromium is a typical heavy metal pollutant, which exists in trivalent and hexavalent chromium compounds in nature, and hexavalent chromium(VI) is more toxic. Chromium(VI) is highly carcinogenic and can cause liver cirrhosis, Reproductive system diseases [1], and other diseases, which pose a serious threat to human health [2]. Chromium(VI) mainly exists in the form of Cr 2 O 7 2− , which has strong oxidizing and fluidity, causing serious pollution to soil and water source [3].…”

Section: Introductionmentioning

confidence: 99%

Fluorescent sensing platform based on polyethyleneimine‐protected copper nanoclusters for detection of chromium(VI) in real samples

Gan,

Wang,

Wang

et al. 2024

Luminescence

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A new type of polyethyleneimine‐protected copper nanoclusters (PEI‐CuNCs) is favorably developed by a one‐pot method under mild conditions. The obtained PEI‐CuNCs is characterized by X‐ray diffraction, X‐ray photoelectron spectroscopy, transmission electron microscopy, Fourier‐transform infrared (FTIR) spectroscopy and other techniques. It is worth noting that the proposed PEI‐CuNCs demonstrate a selective response to chromium(VI) over other competitive species. Fluorescence quenching of PEI‐CuNCs is determined to be chromium(VI) concentrations dependence with a low limit of detection of 8.9 nM. What is more, the as‐developed PEI‐CuNCs is further employed in building a detection platform for portable recognition of chromium(VI) in real samples with good accuracy. These findings may offer a distinctive strategy for the development of methods for analyzing and monitoring chromium(VI) and expand their application in real sample monitoring.

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Ameliorative effect of Nigella sativa conjugated silver nanoparticles against chromium-induced hepatotoxicity and renal toxicity in mice

Cited by 10 publications

References 61 publications

Antibacterial and Wound Healing Efficacy of Silver Nanoparticles Synthesized from Root Bark ofBerberis lyciumRoyle

Antibacterial and Wound Healing Efficacy of Silver Nanoparticles Synthesized from Root Bark ofBerberis lyciumRoyle

Use of Nanoparticles as Antioxidant Agents to Combat Bacterial Infections and its Benefits to Intestinal Microbiota and Immune Response

Fluorescent sensing platform based on polyethyleneimine‐protected copper nanoclusters for detection of chromium(VI) in real samples

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