Ameliorative effect of parsley oil (Petroselinum crispum) against alcohol-induced hepatotoxicity and oxidative stress

Seif, Howida S. Abou

doi:10.1097/01.mjx.0000457175.74392.0b

Cited by 4 publications

(2 citation statements)

References 43 publications

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“…Similarly, other spices plants such as Petroselinum crispum (parsley oil) [ 186 ], clove ( Syzygium aromaticum L.) [ 187 ], Thymus vulgaris [ 188 ], and peppers [ 189 ] were also documented to possess a beneficial effect against alcohol-induced liver injury.…”

Section: Multicomponent Food Plant Extracts Against Aldmentioning

confidence: 99%

Protective Mechanism of Edible Food Plants against Alcoholic Liver Disease with Special Mention to Polyphenolic Compounds

et al. 2021

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Alcoholic liver disease (ALD) is one type of liver disease, causing a global healthcare problem and mortality. The liver undergoes tissue damage by chronic alcohol consumption because it is the main site for metabolism of ethanol. Chronic alcohol exposure progresses from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which further lead to fibrosis, cirrhosis, and even hepatocellular cancer. Therapeutic interventions to combat ALD are very limited such as use of corticosteroids. However, these therapeutic drugs are not effective for long-term usage. Therefore, additional effective and safe therapies to cope with ALD are urgently needed. Previous studies confirmed that edible food plants and their bioactive compounds exert a protective effect against ALD. In this review article, we summarized the hepatoprotective potential of edible food plants and their bioactive compounds. The underlying mechanism for the prevention of ALD by edible food plants was as follows: anti-oxidation, anti-inflammation, lipid regulation, inhibition of apoptosis, gut microbiota composition modulation, and anti-fibrosis.

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Section: Multicomponent Food Plant Extracts Against Aldmentioning

confidence: 99%

Protective Mechanism of Edible Food Plants against Alcoholic Liver Disease with Special Mention to Polyphenolic Compounds

et al. 2021

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“…Bioactive compounds of parsley, such as oleic acid, D-limonene, α-pinene and myristicin have antioxidant properties and thus are able to scavenge free radicals (Farag et al, 2021). Although the immune boosting impacts of parsley have been indicated in some vertebrates (Karimi et al, 2012;Aljanaby, 2013;Abou Seif, 2014;Maodaa et al, 2016;Ashry et al, 2021), this function has been rarely studied in fish. This research aimed to determine the potentials of dietary parsley on growth, activity of digestive enzymes, immunity, stress responses and resistance to ammonia-induced stress in the most important farmed fish, rainbow trout.…”

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confidence: 99%

Ameliorating effects of dietary parsley (Petroselinum crispum) on ammonia toxicity in the rainbow trout, Oncorhynchus mykiss: growth, digestive enzymes, immunity, and stress resistance

Hajirezaee,

Sharifi,

Momeninejad

et al. 2024

Annals of Animal Science

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Use of phytobiotics as immunostimulant is increasing in aquaculture. In this study, the immune and growth prompting effects of parsley extract (PUE) were examined in the rainbow trout. In this regard, the various dietary levels of parsley extract (PUE), Petroselinum crispum (0, 0.5, 1.5, 3, and 4.5%) was added to the diet of rainbow trout to assay its potentials on immunity, growth, digestive enzymes, and mitigating ammonia-induced stress. A total of 450 fish (15.43 ±0.06 g; mean ± SE) were distributed into fifteen 300-L fiberglass tanks (30 fish per tank) and fed PUE for 60 days and then challenged with unionized ammonia (0.3 mg/l). According to results, PUE mainly at 3-4.5% levels increased the growth, lipase and protease activities, hemoral and mucusal immune components and liver antioxidant enzymes activities. These effects were kept even after ammonia stress, where the immune components were higher in PUE-treated fish than the control group. Furthermore, the dietary PUE reduced ammonia-related oxidative stress, as of malondialdehyde (MDA) values (as the indicator of lipid peroxidation) decreased in fish fed PUE. The concentrations of liver metabolic enzymes in blood both before and after ammonia stress declined in the fish fed PUE. Our findings demostrated the growth and immune boosting and ammonia-stress mitigating properties of PUE in rainbow trout.

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Essential oils from Apiaceae family (parsley, lovage, and dill)

Cătunescu¹,

Bodea²,

David³

et al. 2023

Essential Oils

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Ameliorative effect of parsley oil (Petroselinum crispum) against alcohol-induced hepatotoxicity and oxidative stress

Cited by 4 publications

References 43 publications

Protective Mechanism of Edible Food Plants against Alcoholic Liver Disease with Special Mention to Polyphenolic Compounds

Protective Mechanism of Edible Food Plants against Alcoholic Liver Disease with Special Mention to Polyphenolic Compounds

Ameliorating effects of dietary parsley (Petroselinum crispum) on ammonia toxicity in the rainbow trout, Oncorhynchus mykiss: growth, digestive enzymes, immunity, and stress resistance

Essential oils from Apiaceae family (parsley, lovage, and dill)

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