Ameliorative effects of Allium cepa Linn. scaly leaves extract on reproductive dysfunctions in streptozotocin-induced diabetic Wistar rats

Adeleye, O.O.; Okoh, Emmanuel E.; Adeleye, Adenike; Mshelbwala, F. M.; Adetomiwa, A. S.; Apantaku, James; Aboajah, N. A.; Durotoye, Ladoke A.; Olukunle, J. O.

doi:10.30704/http-www-jivs-net.811491

Cited by 1 publication

(1 citation statement)

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“…Extracts from AC have been shown to induce a variety of bioactivities, including anti-inflammatory, antioxidant, and anti-diabetic properties. [22,[90][91][92][93] S-methyl cysteine sulfoxide and S-allyl cysteine sulfoxide, which are found in the bulb, have been shown to have anti-diabetic properties [91]. Again many mechanisms can be responsible of the antidiabetic activity but secretagogue effect is the most relevant.…”

Section: Allium Cepa Linnmentioning

confidence: 99%

A Review on the Antidiabetic Potential of Medicinal Plants

Bushnak¹,

Hajj²,

Jaber³

2021

SJMH

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Diabetes mellitus has long been seen as a substantial economic burden on patients, their families, and society. Impairment in blood sugar regulation has major health repercussions. Furthermore, untreated diabetes causes major chronic complications like blindness, renal failure, and heart failure, as well as an increase in associated mortality. New anti-diabetic medicines are being researched to help alleviate this issue. Conventional Anti-diabetic medications are beneficial, several synthetic drugs are available in the market to treat diabetes, but they are costly and come with inevitable adverse effects. Medicinal plants, on the other hand, may serve as an alternate source of anti-diabetic agents. According to the World Health Organization, 80 % of the population in underdeveloped nations still relies on traditional medicines or folk medicines, which are largely made from plants, for disease prevention or treatment. For instance, anti- proliferative, anti-viral, anti-inflammatory and anti-hyperglycemic effects. In order to find a natural anti-diabetic source that comes with less side effects, several studies have been conducted. The aim of this work is to review these studies and highlight the potential of plants when it comes to their anti-diabetic effect.

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