Ameliorative effects of ethanolic constituents of Bangladeshi propolis against tetracycline‐induced hepatic and renal toxicity in rats

Tanvir, E. M.; Hasan, Md. Asif; Nayan, Shariful Islam; Islam, Tamanna; Ahmed, Tania; Hossen, Md. Sakib; Perveen, Rasheda; Rahman, Shahnaz; Afroz, Raihana; Afroz, Rizwana; Chowdhury, M. A. Z.

doi:10.1111/jfbc.12958

Cited by 10 publications

(6 citation statements)

References 40 publications

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“…Tetracycline (TC) is a bacteriostatic agent that inhibits the synthesis of bacterial protein and is widely used as an antibiotic for animals and humans. 12 However, only a small part of antibiotics can be digested and absorbed after they enter the human body or livestock, and most of these compounds are discharged from the body through feces. Improperly treated TC in wastewater can become an important source for aqueous solution and soil pollution and can have harmful effects on human health.…”

Section: Introductionmentioning

confidence: 99%

Removal of Tetracycline from Water Using Activated Carbon Derived from the Mixture of Phragmites australis and Waterworks Sludge

Zhao

Yin

et al. 2020

ACS Omega

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Sludge-based activated carbon with doped Phragmites australis was prepared using an environment-friendly method to treat waterworks sludge (WS) and obtain an economical adsorbing material for tetracycline (TC) elimination. For the WS, P. australis was used as an additive to optimize the preparation of activated carbon. Optimum preparation conditions were as follows: activation temperature, 600 °C; ZnCl 2 concentration, 3 mol/L; activation time, 50 min; impregnation ratio (weight of mix sample: weight of ZnCl 2 ) of 1:2.5; and the mixed ratio of P. australis with WS, 40%. The obtained activated carbon owned well-developed Brunauer−Emmett−Teller surface area (949.90 m 2 /g). The acidic and basic functional groups were improved to 0.762 and 0.016 mmol/g, respectively. The pseudo-second-order kinetic and Freundlich isotherm equations were more suitable models to simulate adsorption with the maximum adsorption capacity of 153.4 mg/g. According to the thermodynamic parameters, the adsorption process was spontaneous and endothermic. Electrostatic interaction, hydrogen bonding formation, and ion complexation adsorption mechanisms were the mechanisms underlying the adsorption of TC.

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Section: Introductionmentioning

confidence: 99%

Removal of Tetracycline from Water Using Activated Carbon Derived from the Mixture of Phragmites australis and Waterworks Sludge

Zhao

Yin

et al. 2020

ACS Omega

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“…Propolis is also rich in flavonoids such as naringin, pinocembrin, naringenin, acacetin, quercetin, chrysin and luteolin. In addition, a study (Tanvir et al 2019). using ethanol extract in Bangladeshi propolis identified compounds including tannin acid, gallic acid, catechins, pyrogallol, naringin, quercetin and many more.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of Honey Bees Propolis Extract in The Treatment of Type 1 Diabetes Mellitus

Nisa,

Kustiawan

2023

JFG

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Background: Diabetes Mellitus (DM) is a health problem that affects more than 400 million people worldwide. Type 1 diabetes is an autoimmune disease characterized by damage of pancreatic cells followed by hyperglycemia and oxidative stress. Propolis is one of the natural ingredients of bee products. Propolis is known to have bioactive compounds that are rich in flavonoids, phenolic and antioxidant properties so that it has potential as an antidiabetic. Objectives: This writing aims to determine the activity of propolis in test animals of Type 1 DM model. Material and Methods: This research method uses a literature study using type 1 diabetic as inclusion criteria in journal screening. Keywords used include propolis, diabetes and hyperglycemia. Literature is obtained through an electronic data base, such as Google Scholar, PubMed, Scopus and Science Direct. Results: Based on the articles that have been collected, that Type 1 DM causes inflammation which is characterized by decreased immune function due to increased levels of IL-6, IL-1β and TNF-α. Propolis can reduce levels of pro-inflammatory cytokines, prevent the inflammatory process in diabetes and have hypoglycemic activity. Conclusions: The conclusion of the reviewed article that propolis from honey bee has effectiveness to improve the function of body cells and reduce diabetes complication.

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“…Oral administration to TCs produced critical hepatic and renal injury as indicated by significant changes in liver marker enzymes in rat serum: bilirubin and protein concentrations, lipid profile, and markers of kidney function when compared with controls. [ 46 ]…”

Section: Discussionmentioning

confidence: 99%

Influence of doxycycline administration on rat embryonic development during organogenesis

Abd-Allah

El‐Rahman

2020

J Biochem & Molecular Tox

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This experiment was performed to evaluate the possible embryotoxic and teratogenic effects of doxycycline during rat development. Twenty‐one female rats were used and distributed into three groups equally (seven animals/group). The low dose group received doxycycline at a dose of 5 mg/kg bw/day orally from the 6th to 14th day of gestation. The high dose group received 10 mg/kg bw/day orally for the same period, the Control group received 1 mL distilled water orally for the same period. The dams were dissected on the 20th day of gestation and their fetuses were subjected to morphological, skeletal, and histological examination. Moreover, DNA damage analysis of liver cells of pregnant rats and their fetuses or fetal skull was assessed by Comet assay. The obtained results showed a significant decrease in fetal body weight, several morphological anomalies, and severe lack of ossification on the skull bones, phalanges, and sternum bone as well as shortness in the ulna and radius bones. Histological studies of pregnant rats revealed congestion and dilatation of the central vein of the liver lobules and fatty degeneration of the hepatocytes. In addition, 20 day‐fetuses showed a marked increase of necrotic hepatocytes associated with an increased average of megakaryocytes and periportal leukocytic infiltration. Moreover, doxycycline induced a significant increase in the percentage of DNA damage and tail length of examined samples. Conclusively, doxycycline caused certain fetal abnormalities, so it is advisable to avoid using this drug during pregnancy.

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Ameliorative effects of ethanolic constituents of Bangladeshi propolis against tetracycline‐induced hepatic and renal toxicity in rats

Cited by 10 publications

References 40 publications

Removal of Tetracycline from Water Using Activated Carbon Derived from the Mixture of Phragmites australis and Waterworks Sludge

Removal of Tetracycline from Water Using Activated Carbon Derived from the Mixture of Phragmites australis and Waterworks Sludge

Effectiveness of Honey Bees Propolis Extract in The Treatment of Type 1 Diabetes Mellitus

Influence of doxycycline administration on rat embryonic development during organogenesis

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