Ameliorative Role of Bee Honey and Royal Jelly Against Cisplatin Induced Alteration in Hematological Parameters in Male Wister Albino Rat

Bhalchandra, Waykar; Alqadhi, Yahya Ali; Ninawe, A S

doi:10.22159/ijpps.2018v10i4.23153

Cited by 6 publications

(6 citation statements)

References 42 publications

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“…However, Morita et al [53] reported that there is a lack of articles that interpret the effect of RJ on anaemia. Recently, Bhalchandra et al [54] reported that intraperitoneal injection of RJ in rats improved Hb concentrations and mean corpuscular haemoglobin (MCH) and suggested that honey and RJ exert protective effects against blood cell damage via preservation of cellular integrity. Our findings suggest that RJ feeding might have an anti-anaemic effect.…”

Section: Discussionmentioning

confidence: 99%

Does in Ovo Injection of Two Chicken Strains with Royal Jelly Impact Hatchability, Post-Hatch Growth Performance and Haematological and Immunological Parameters in Hatched Chicks?

Taha

AbdAllah

Attia

et al. 2019

Animals

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Simple SummaryThe present investigation examined improvements in egg hatchability and the growth performance of hatched chicks of two strains upon injection with increasing concentrations of royal jelly (RJ). The results showed positive effects of RJ injection on all parameters. Limited impacts of the different chicken strains were observed on the tested parameters. The study revealed that varying the chicken strain could alter the response to the in ovo injection with RJ.AbstractThe hypothesis of the present work was that the effects of in ovo injection may differ in different chicken strains. The influence of in ovo royal jelly (RJ) injection on hatching, growth and blood parameters in two chicken strains (Dokki-4 and El-Salam as example for different strains) was evaluated. A total of 1080 eggs were used. On the seventh day of incubation, the eggs were randomly allocated into six experimental groups in a 2 × 3 arrangement that included the two chicken strains and three concentrations of RJ (0, 0.25 and 0.5 mL RJ/egg). Injection with 0.5 mL RJ/egg improved hatchability compared to the other treatments. The El-Salam strain exhibited significantly higher body weight and body weight gain than the Dokki-4 strain. Injection with 0.5 mL RJ/egg significantly (p < 0.05) improved chicken body weight and daily weight gain compared to the control treatment. RJ injection decreased blood lipid profile parameters and the numbers of monocytes and eosinophils and increased total protein, globulin, haemoglobin (Hb) and lymphocyte levels compared to the control treatment. The Dokki-4 strain showed significantly higher antibody titres against avian influenza virus (AIV) (p < 0.05) and sheep red blood cells (SRBCs) (p < 0.0001) than the El-Salam strain and RJ injection enhanced antibody titres against AIV, Newcastle disease virus (NDV) and SRBCs. Therefore, the Dokki-4 strain was superior to the El-Salam strain for the tested parameters and injection with 0.5 mL RJ/egg produced the best hatching parameters, growth performance and health-related traits. RJ in ovo injection was much more effective in the Dokki-4 strain than in the El-Salam strain, which supported the hypothesis of the study that varying the chicken strain could alter the response to the in ovo injection with RJ.

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Section: Discussionmentioning

confidence: 99%

Does in Ovo Injection of Two Chicken Strains with Royal Jelly Impact Hatchability, Post-Hatch Growth Performance and Haematological and Immunological Parameters in Hatched Chicks?

Taha

AbdAllah

Attia

et al. 2019

Animals

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“…Flavonoids containing bioactive compounds maintained WBC counts due to their free radical scavenging property [23,22]. It is reported that honey and royal jelly showed significant protective effect on hematological variables [33] because they contain several bioactive compounds. Rutin administration maintained these hematological variables might be due to their antioxidant activity [7].…”

Section: Discussionmentioning

confidence: 99%

Effect of Rutin Against High-Fat Diet and Alcohol-Induced Alterations in Hematological Variables of Rats

Chandra

Mishra

Sahu

et al. 2018

Asian J Pharm Clin Res

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Objectives: Alcohol abuse leads to several diseases and millions of death worldwide. High-fat diet (HFD) is major contributor of non-alcoholic liver diseases and obesity. Combined consumption of HFD and alcohol has deleterious effect on blood cells. This study was carried out to evaluate the protective effect of rutin against combined consumption of HFD and alcohol-induced hematological alterations.Methods: HFD 30% and ethanol 10% were administered for 4 weeks for induction of toxicity. Rutin (10, 20, and 40 mg/kg) and 50 mg/kg dose of silymarin were administered along with HFD and alcohol for 4 weeks.Results: Combined consumption of HFD and alcohol increased mean corpuscular volume, total leukocytes count, eosinophil and monocyte, and decreased hematocrit and platelets. Administration of rutin improved hematological variables altered by HFD and alcohol consumption.Conclusion: The present study concluded that administration of rutin may alleviate HFD and alcohol-induced hematological alterations by scavenging free radicals generation.

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“…The treatment with beebread and honey might have protected blood cells from pathological consequences of free radical induced membrane lipid peroxidation such as increased membrane rigidity, decreased cellular deformability, reduced erythrocyte survival, and lipid fluidity (Bhalchandra et al, 2018) because they contain flavonoids, such as quercetin and rutin, which exert strong activity against oxidative damage and inflammatory response (Zuluaga et al, 2015).…”

Section: Red Blood Cell Count Haemoglobin Concentration and Packed Ce...mentioning

confidence: 99%

Beebread and Honey improves some Haematologic Parameters in Male ‎Albino Mice

Igbokwe,

Omeh,

Kashim

2022

SJVS

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The effects of honey and beebread on some haematological parameters were investigated in fifteen apparently healthy adult albino male mice. The mice were divided into three groups of five mice each after a two-week period of acclimatization. The mice in group A were given distilled water orally to serve as a control while those in groups B and C were administered honey and beebread respectively by gavages at the dose rate of 1g/kg body weight and at a concentration of 40% w/v using water as a vehicle, once daily for 70 consecutive days. Micro-haematocrit and hematocytometry were used for determination of packed cell volume and erythrocyte and differential leucocyte counts, respectively. Haemoglobin concentration was estimated by using Cyanmethemoglobin method. There were significant (p ˂0.05) increases in the red blood cells count, packed cell volume and haemoglobin concentration in the treatment groups compared to the control group, with the most increase observed in the group treated with beebread. There was significant (p ˂ 0.05) increase in total leucocyte count in the treated groups with the highest count recorded in the honey treated group than the control. Lymphocytes and neutrophils significantly (p ˂ 0.05) increased in the treatment groups but there were no significant (P > 0.05) changes in the number of eosinophils, basophils and monocytes. The study demonstrates the positive haematopoietic effects of supplementation of feed with honey and beebread.

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Ameliorative Role of Bee Honey and Royal Jelly Against Cisplatin Induced Alteration in Hematological Parameters in Male Wister Albino Rat

Cited by 6 publications

References 42 publications

Does in Ovo Injection of Two Chicken Strains with Royal Jelly Impact Hatchability, Post-Hatch Growth Performance and Haematological and Immunological Parameters in Hatched Chicks?

Does in Ovo Injection of Two Chicken Strains with Royal Jelly Impact Hatchability, Post-Hatch Growth Performance and Haematological and Immunological Parameters in Hatched Chicks?

Effect of Rutin Against High-Fat Diet and Alcohol-Induced Alterations in Hematological Variables of Rats

Beebread and Honey improves some Haematologic Parameters in Male ‎Albino Mice

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