Ameloblastic Fibro-Odontoma: A Clinicopathologic Study of 12 Cases

Abstract

The opinions and assertions expressed herein are those of the authors and are not to be construed as official or as reflecting the views of the Department of the Air Force or the Department of Defense. Objective: The ameloblastic fibro-odontoma (AFO) is an uncommon odontogenic tumor occurring in childhood with limited reported data on recurrence. The purpose of this AFO study was to review its clinicopathologic features, investigate treatment modalities and establish a recurrence rate. Study Design: The clinicopathologic features of 12 new cases of AFO were analyzed and compared with those of 208 cases from the literature, with special emphasis on the clinical behavior, treatment, and recurrence rate. Results:The average age was 9.4 (±6.7) years with a male-to-female ratio of 1.6:1. The mandible was the site of occurrence in 59.5%. The tumor most often presented radiographically as a unilocular mixed density lesion associated with the crown of an impacted tooth. Displacement of teeth, delayed eruption and bony expansion were commonplace. There were 5 recurrences among 68 cases with adequate follow-up for a recurrence rate of 7.4%. All recurrences were attributed to incomplete removal at the time of the initial surgery.Conclusions: The AFO is a childhood tumor most often affecting the posterior jaws and frequently causing bony expansion with profound affects on the dentition. Conservative surgical removal with extraction of the associated teeth is recommended. The established recurrence rate is less than 10%.

Ameloblastic fibro-odontoma: case report

“…Boxberger et al 4 , Buchner et al 7 and Zouhary et al 8 affirmed that this tumor presented predilection for the male sex, however, the World Health Organization and authors such as Nelson & Thompson 5 , Hunter et al 9 and Lúcio et al 10 affirmed that there was no predilection for gender or localization.…”

“…According to De Riu et al 11 and Tolentino et al 12 , the tumor may inhibit eruption of the tooth involved. In the present case, agenesis of tooth 38 was diagnosed, and the tumor had not affected tooth 37, which was found in the routine panoramic radiograph taken for the purpose of having third molars extracted [3][4] .…”

“…Because AFO is asymptomatic, it is normally only diagnosed when the patient has a routine panoramic radiograph taken, or when the parents perceive that eruption of some tooth is delayed [3][4] . Cavalcante et al 13 related that the increase in volume is also a reason for the children's families to seek dentists, although the studies of Boxberger et al 4 showed that only a small portion of the cases presented expansion.…”

“…Cavalcante et al 13 related that the increase in volume is also a reason for the children's families to seek dentists, although the studies of Boxberger et al 4 showed that only a small portion of the cases presented expansion.…”

“…The ameloblastic fibro-odontoma (AFO) is an uncommon, mixed odontogenic tumor that represents from 1 to 3% of all the odontogenic tumors [1][2][3][4][5] and could be confused with various lesions. It is of significant importance due to its potential for growth.…”