Ameloblastoma: a multicentric study

Dhanuthai, Kittipong; Chantarangsu, Soranun; Rojanawatsirivej, Somsri; Phattarataratip, Ekarat; Darling, Mark; Jackson-Boeters, Linda; Said-Al-Naief, Nasser; Shin, Hong In; An, Chang Hyeong; Hồng, Nguyễn Thị; An, Phan Huynh; Thosaporn, Watcharaporn; Lam‐ubol, Aroonwan; Subarnbhesaj, Ajiravudh

doi:10.1016/j.oooo.2012.01.011

Cited by 71 publications

(75 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[8] Multicentric study by Dhanuthai et al ., reported the same percentage to be 42%. [9] In another study of ameloblastomas in young patients (below 20 years) by Kahn et al ., the percentage of unilocular ameloblastomas was 72%. [10] Mohamed et al ., in their review concluded that most of AOT were round to oval and well demarcated.…”

Section: Discussionmentioning

confidence: 99%

Unilocular radiolucencies of anterior mandible in young patients: A 10 year retrospective study

Mohanty

Gulati

Mediratta³

et al. 2013

Natl J Maxillofac Surg

View full text Add to dashboard Cite

Introduction:Mandibular anterior region is an uncommon site for occurrence of intrabony pathologies. Unilocular presentation of a lesion is again less common than multilocular appearance. Demographically, most lesions occur in middle to elderly age group. The study is designed to review the pathologies manifesting a combination of these rare demographic and radiological criteria.Materials and Methods:A retrospective analysis of patients with anterior unilocular radiolucencies of mandible in young patients was done. Records of past 10 years were searched. There were a total of 17 patients. Their clinical history and radiographs were reviewed from the case files and correlated with histopathological examination of the lesion.Results:Nine different pathologies constituted the sample size of 17. A wide array of lesions was found to manifest similar signs and symptoms and radiographic findings namely ameloblastoma (three), adenomatoid odontogenic tumor (AOT, four), odontogenic keratocyst (OKC, three), ossifying fibroma (OF, two), idiopathic bone cavity (IBC, one), dentigerous cyst (DC, one), radicular cyst (RC, one), central giant cell granuloma (CGCG, one), and calcifying odontogenic cyst (COC, one).Conclusion:Anterior mandible is a rare site for occurrence of intrabony pathologies. Majority of patients are females. Lesions acquire large size before they are detected. Growth occurs more in length than in width. Root resorption is not uncommon and root displacement is almost a consistent feature.

show abstract

Section: Discussionmentioning

confidence: 99%

Unilocular radiolucencies of anterior mandible in young patients: A 10 year retrospective study

Mohanty

Gulati

Mediratta³

et al. 2013

Natl J Maxillofac Surg

View full text Add to dashboard Cite

show abstract

“…A total of 5,213 cases of ameloblastomas are found in literature, including 3,677 cases of ameloblastomas available in literature from 1960 to 1993,5 340 cases of ameloblastomas in the Malaysian population (1993 through 2008),6 and 1,196 cases of ameloblastomas diagnosed during the years of 1993 to 2009 in Chulalongkorn University, Bangkok 7. These studies revealed the mean age of patients as 36.1 years, with 2,709 (51.9%) patients being male, and mandibular tumors (81.7%) outnumbering maxillary tumors.…”

Section: Ameloblastomamentioning

confidence: 99%

Current Concepts and Occurrence of Epithelial Odontogenic Tumors: I. Ameloblastoma and Adenomatoid Odontogenic Tumor

Lee

Kim

2013

Korean J Pathol

View full text Add to dashboard Cite

Ameloblastomas and adenomatoid odontogenic tumors (AOTs) are common epithelial tumors of odontogenic origin. Ameloblastomas are clinico-pathologically classified into solid/multicystic, unicystic, desmoplastic, and peripheral types, and also divided into follicular, plexiform, acanthomatous, granular types, etc., based on their histological features. Craniopharyngiomas, derived from the remnants of Rathke's pouch or a misplaced enamel organ, are also comparable to the odontogenic tumors. The malignant transformation of ameloblastomas results in the formation of ameloblastic carcinomas and malignant ameloblastomas depending on cytological dysplasia and metastasis, respectively. AOTs are classified into follicular, extrafollicular, and peripheral types. Ameloblastomas are common, have an aggressive behavior and recurrent course, and are rarely metastatic, while AOTs are hamartomatous benign lesions derived from the complex system of the dental lamina or its remnants. With advances in the elucidation of molecular signaling mechanisms in cells, the cytodifferentiation of epithelial tumor cells in ameloblastomas and AOTs can be identified using different biomarkers. Therefore, it is suggested that comprehensive pathological observation including molecular genetic information can provide a more reliable differential diagnosis for the propagation and prognosis of ameloblastomas and AOTs. This study aimed to review the current concepts of ameloblastomas and AOTs and to discuss their clinico-pathological features relevant to tumorigenesis and prognosis.

show abstract

“…Ameloblastoma represents about 1% of all tumors and cysts of the jaws, and 13%–78% of all odontogenic tumors (Junquera, Ascani, Vicente, Garcia‐Consuegra, & Roig, ). Ameloblastoma is a locally invasive benign tumor of epithelial origin that may grow from rests of dental lamina, enamel apparatus, the epithelial lining of an odontogenic (dentigerous) cyst, or from the basal epithelial cells of the oral mucosa (Dhanuthai et al, ). It often manifests clinically as a slow‐growing, painless swelling, causing expansion of cortical bone, spreading of the lingual and/or buccal plates, and penetration of soft tissue.…”

Section: Introductionmentioning

confidence: 99%

Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta‐analysis

et al. 2019

View full text Add to dashboard Cite

Objectives The aim of the present study was to assess the outcomes of radical and conservative treatment approaches of solid/multicystic and unicystic ameloblastoma in terms of recurrence rates. Material and methods A systematic review and meta‐analysis was conducted based on the PRISMA statement. Search was performed using PubMed, Embase, SCOPUS, and Web of Science for articles published from January 1969 until March 2018. Quality assessment of the selected articles was conducted using the Quality Appraisal of Case Series Studies Checklist. The meta‐analysis was performed using the MedCalc program. Results The search strategy yielded 6,984 articles; 20 studies met the eligibility criteria and were included in the meta‐analysis. The pooled recurrence rate of solid/multicystic ameloblastomas following radical treatment was 8%, while conservative treatment caused recurrences in 41%. For unicystic ameloblastomas, these values were 3% and 21%, respectively. The risk of recurrences in both types of ameloblastomas following radical treatment was lower than following conservative treatment. Conclusions The present study showed statistically significant differences in recurrence favoring radical treatment for both unicystic and solid/multicystic ameloblastoma. The solid/multicystic type showed more recurrences than the unicystic type. Unfortunately, since only retrospective studies were available, the evidence is less strong as wished for.

show abstract

Ameloblastoma: a multicentric study

Cited by 71 publications

References 34 publications

Unilocular radiolucencies of anterior mandible in young patients: A 10 year retrospective study

Unilocular radiolucencies of anterior mandible in young patients: A 10 year retrospective study

Current Concepts and Occurrence of Epithelial Odontogenic Tumors: I. Ameloblastoma and Adenomatoid Odontogenic Tumor

Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta‐analysis

Contact Info

Product

Resources

About