Ameloblastoma: A retrospective analysis of 31 cases

Giraddi, Girish; Arora, Kirti; Saifi, Aamir Malick

doi:10.1016/j.jobcr.2017.08.007

Cited by 25 publications

(21 citation statements)

References 10 publications

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“…The ameloblastoma is an epithelial neoplasia originating in the enamel and has been described as a tumor that is usually unicentric, intermittent in growth, and persistent [1]. According to the recent classification by the World Health Organization (WHO) [2], ameloblastoma is defined as a benign epithelial odontogenic neoplasia, characterized by tumor expansion, progressive growth, and a tendency for recurrence if not completely removed.…”

Section: Introductionmentioning

confidence: 99%

Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas

Carreon-Burciaga

González-González

Molina-Frechero

et al. 2018

Analytical Cellular Pathology

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Ameloblastomas are a group of benign, locally aggressive, recurrent tumors characterized by their slow and infiltrative growth. E-Cadherin and syndecan-1 are cell adhesion molecules related to the behavior of various tumors, including ameloblastomas. Ninety-nine ameloblastoma samples were studied; the expression of E-cadherin and syndecan-1 were evaluated by immunohistochemistry. E-Cadherin and epithelial syndecan-1 were more highly expressed in intraluminal/luminal unicystic ameloblastoma than in mural unicystic ameloblastoma and solid/multicystic ameloblastoma, whereas the stromal expression of syndecan-1 was higher in mural unicystic ameloblastoma and solid/multicystic ameloblastoma. Synchronicity was observed between E-cadherin and epithelial syndecan-1; the expression was correlated with intensity in all cases. There was a strong association between expression and tumor size and recurrence. The evaluation of the expression of E-cadherin and syndecan-1 are important for determining the potential aggressiveness of ameloblastoma variants. Future studies are required to understand how the expression of these markers is related to tumor aggressiveness.

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Section: Introductionmentioning

confidence: 99%

Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas

Carreon-Burciaga

González-González

Molina-Frechero

et al. 2018

Analytical Cellular Pathology

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“…Em um estudo retrospectivo com 31 casos, pesquisadores trataram os AUs luminal e intraluminal por enucleação, enquanto a ressecção cirúrgica foi reservada para AUs invasivos e murais. Visto que nenhum dos casos recidivou durante o acompanhamento de até 7 anos, os autores recomendaram que este mesmo protocolo fosse considerado nos tratamentos de AU 7 . Em outro estudo, os autores decidiram tratar todos os pacientes com enucleação e osteotomia periférica.…”

Section: Discussionunclassified

“…Frequentemente, essas lesões são diagnosticadas em período inicial, em fase de crescimento lento, quando não provocam sinais e sintomas ou apenas ocasionam aumento de volume 6 . Entretanto, o crescimento tardio do tumor é acelerado e pode ocasionar desordens neurossensoriais, dor, assimetria facial, dificuldades de mastigação e fonação, desordens oclusivas e perdas dentárias 7 .…”

Section: Introductionunclassified

Extenso ameloblastoma unicístico em mandíbula: relato de caso

Silva

Santos

Rodrigues

et al. 2019

Rev. da Fac. de Odontologia, UPF

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Objetivo: Relatar um caso de Ameloblastoma Unicístico em região anterior de mandíbula, descrevendo os métodos diagnósticos utilizados e o tratamento empregado. Relato de Caso: Paciente do gênero feminino, 40 anos de idade, compareceu ao serviço de Cirurgia e Traumatologia Bucomaxilofacial da Faculdade de Odontologia da Universidade Federal da Bahia, com queixas de aumento de volume em região anterior de mandíbula, com evolução de 10 meses. O exame de imagem revelou lesão unilocular extensa que expandia cortical óssea em região de mento. Optou-se pela biópsia excisional da lesão, sob anestesia geral. O exame o espécime obtido confirmou o diagnóstico de Ameloblastoma Unicístico, para o qual decidiu-se pela manutenção da terapêutica inicial. A paciente segue em acompanhamento pela equipe, sem sinais de recidivas. Considerações Finais: O manejo do Ameloblastoma Unicístico por vezes demanda a biópsia excisional da lesão a fim de diferencia-la dos cistos odontogênicos e de individualizar seu padrão histológico. A abordagem conservadora pode ser adotada, desde que um acompanhamento rigoroso seja procedido.

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“…Management of UA varies accordingly. The management of ameloblastoma is dependent on factors such as clinical type, location in the jaws, age of patient; associated morbidity and availability for follow up examinations (6,7). Although conservative management has been advocated for most cases of UA, the mural variant is associated with high recurrence and should be treated like a solid ameloblastoma (2) Based on their study results, Girradi et al (7) have recommended surgical resection for solid multicystic, desmoplastic and invasive and mural invasive unicystic ameloblastomas, and enucleation for luminal and intraluminal unicystic ameloblastomas while others recommend that curettage should be done only for unicystic ameloblastomas of the anterior mandible (8).…”

Section: Letter To the Editormentioning

confidence: 99%

Cone Beam Computed Tomographic findings in Unicystic Ameloblastoma of the mandible.

G¹,

Ajila²,

Hegde³

et al. 2018

J Turgut Ozal Med Cent

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Ameloblastomas are one of the commonly encountered odontogenic tumours (1). Ameloblastomas are of the following types namely peripheral, solid or multicystic, unicystic, desmoplastic, and malignant (1,2). Unicystic ameloblastoma is a rare variant of ameloblastoma and accounts for around 6% of all ameloblastomas (1). Clinically and radiographically, it resembles a cyst but on histopathological examination has features of ameloblastoma (1). Cases with multilocular radiolucency and histopathology of unicystic ameloblastomas were earlier termed as cystic ameloblastomas. However, this term is no longer used; instead, the lesions are termed as unicystic ameloblastoma (1). The present case describes unicystic ameloblastoma of the posterior mandible in a 42 years old male patient. A 42 years-old-male reported to our department with complaint of pain in the lower left back tooth region last 15 days. He gave history of a fall two weeks previously followed by continuous, throbbing, diffuse pain in the area of the lower jaw and on the right side of the face, radiating till the right ear. There was mild swelling and difficulty in eating and wide opening of the mouth. He consulted a dental practitioner who prescribed antibiotics and advised a panoramic radiograph. Panoramic radiograph showed a well-defined radiolucent lesion approximately 2x4 cms in size located distal to the mandibular left third molar. He was then referred to our institution.Extraoral examination showed no abnormalities. On intraoral examination, a bluish white swelling approximately 1x1cms in size was present from distal and lingual to the crown of the mandibular left third molar. On palpation, the swelling was soft in consistency and non-tender. The third molar appeared to be displaced buccally due to the swelling ( Figure 1A). The second and third molars were vital on electric pulp testing. Panoramic radiograph showed a well-defined radiolucency approximately 3x4 cms in size distal to the mandibular left third molar. Superiorly the radiolucency extended to the alveolar crest and inferiorly, it surrounded the distal root of the third molar with evidence of root resorption. Medially the swelling was along the distal surface of the third molar and laterally extended around 4 cm distal to the third molar. There were no calcifications or loculations within the radiolucency ( Figure 1B).

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Ameloblastoma: A retrospective analysis of 31 cases

Cited by 25 publications

References 10 publications

Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas

Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas

Extenso ameloblastoma unicístico em mandíbula: relato de caso

Cone Beam Computed Tomographic findings in Unicystic Ameloblastoma of the mandible.

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