Purpose: The aim of present study was to study the effect of
osteopathic manipulation on pain relief and quality of life improvement in
hospitalized oncology geriatric patients. Methods: A nonrandomized
controlled clinical trial was performed in the Oncology Rehabilitation Unit,
Milan, Italy, from September 2015 to March 2016. Twenty-three older cancer
patients were enrolled and allocated in 2 experimental groups: the study group
(OMT group, N = 12) underwent osteopathic manipulative treatment in addition to
physiotherapy, and the control group (PT group, N = 12) underwent only
physiotherapy. At enrollment (T0), 24 recruited oncology patients completed the
sociodemographic forms and were evaluated for pain intensity and quality of life
by an external examiner. All patients were revaluated every week (T1, T2, T3,
and T4) for pain intensity and at the end of the study treatment (T4) for
quality of life. A standard level of significance was set at α < .05.
Results: The 2 groups did not significantly differ in age
(P = .682), body mass index (P = .413), or
gender (P = 1). The osteopathic manipulative treatment added to
physiotherapy produced a significant reduction in Numeric Rating Scale (NRS)
scores both at T2 (P = .004) and T4 (P =
.002). The difference in quality of life improvements between T0 and T4 was not
statistically significant. NRS improved in the PT group at T4. Between-group
analysis of NRS and quality of life with the Mann-Whitney test did not show any
significant difference between the 2 treatments. Conclusions: Our
study showed a significant improvement in pain relief and a nonsignificant
improvement in quality of life in hospitalized geriatric oncology patients
during osteopathic manipulative treatment. Trial Registration:
Protocol registered on Clinicaltrials.gov
(NCT03142386).