Encyclopedia of Life Sciences 2020
DOI: 10.1002/9780470015902.a0029204
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Amino Acid Biosynthesis

Abstract: Amino acids are classically considered as the building blocks for the synthesis of proteins. The unique characteristics of amino acids are the presence of a free amino group in the α‐carbon and a free carboxyl group. The amino acids differ from each other with respect to their side‐chains and are classified into subgroups according to their similarity in carbon skeleton, substituent groups or a common metabolic pathway. The biosynthesis of amino acids involves several biochemical pathways in which amino acids … Show more

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Cited by 2 publications
(3 citation statements)
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“…The synthesis of AAs in humans comprises several pathways in which AAs are built from other precursors. The carbon skeletons of AAs are derived from seven intermediates, which are found in the glycolytic, pentose phosphate and citrate cycle pathways [ 3 ].…”
Section: Introduction: Why We Need Proteins Of a High Biological Vmentioning
confidence: 99%
See 1 more Smart Citation
“…The synthesis of AAs in humans comprises several pathways in which AAs are built from other precursors. The carbon skeletons of AAs are derived from seven intermediates, which are found in the glycolytic, pentose phosphate and citrate cycle pathways [ 3 ].…”
Section: Introduction: Why We Need Proteins Of a High Biological Vmentioning
confidence: 99%
“…Therefore, these AAs are synthesized at rates in excess of their needs for protein synthesis. However, for other AAs, such as arginine and tyrosine, fluxes are close to their concentrations in proteins, indicating much lower synthesis rates [ 3 , 8 , 9 , 10 ]; therefore, their body production may be insufficient in conditions characterized by increased AA demand (such as sepsis, acute kidney injury etc.).…”
Section: Introduction: Why We Need Proteins Of a High Biological Vmentioning
confidence: 99%
“…Ο κυτταρικός μεταβολισμός, ο πολλαπλασιασμός και οι άλλες λειτουργίες των κυττάρων βασίζονται στη δραση τους. (187,188) ενωθούν για να δημιουργηθούν οι πρωτεΐνες. Πηγή ενέργειας για όλα τα στάδια της πρωτεϊνοσύνθεσης και της βιοσύνθεσης των αμινοξέων είναι τα μικρά μόρια (ATP, GTP) που προέρχονται από τη γλυκόλυση.…”
Section: μεταβολομική ανάλυσηunclassified