Amino Acid-Functionalized Electrochemically Reduced Graphene Oxide-Modified Glassy Carbon Electrodes for the Efficient Sensing of Nitrite

Abstract

The sensing capabilities of the modified electrodes were characterized by electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV). The comparative results indicated the outstanding performance of L-histidine with an enhanced electrochemical signal for nitrite due to its powerful imidazole groups, π-π interactions and lone pair-π interactions.

Development of a Cu@ERGO-p(L-Lys) Modified GCE Electrochemical Sensor for the Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid

“…Thus, amino acids that were electro-polymerized on the electrodes by a combination of -NH 2 and -COOH have attracted the attention of researchers for the construction of biosensors. 30,31 Lys can interact electrostatically with the negatively charged groups of GO. 31 Furthermore, the carboxyl groups of GO can readily interact with the amine group of the amino acid, and the p(L-Lys)-ERGO composite exhibits the properties of each component in a synergistic manner.…”