“…Moreover, although such recommendations appear reasonable from a nitrogen-balance point of view, especially given the loss of amino acids during CRRT [21,22,23,24,25,26,27], the only randomized controlled trial focusing on clinical outcomes was conducted in 1973 [28] and has little relevance to modern practice. Moreover, recent investigations have suggested that permissive underfeeding, trophic feeding, or delayed parenteral feeding may be equivalent or perhaps superior to currently recommended approaches [29,30,31,32].…”