2000
DOI: 10.1097/00003246-200004000-00041
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Amino acid loss and nitrogen balance in critically ill children with acute renal failure: A prospective comparison between classic hemofiltration and hemofiltration with dialysis

Abstract: Clearance of AA is greater on CVVH than on CVVHD, but no significant difference in AA loss was present between the two therapies. Nitrogen balance often is not met on either therapy when a standard 1.5 g/kg/day protein and a resting energy expenditure of 120% to 130% of calories is delivered by TPN.

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Cited by 153 publications
(85 citation statements)
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“…Moreover, although such recommendations appear reasonable from a nitrogen-balance point of view, especially given the loss of amino acids during CRRT [21,22,23,24,25,26,27], the only randomized controlled trial focusing on clinical outcomes was conducted in 1973 [28] and has little relevance to modern practice. Moreover, recent investigations have suggested that permissive underfeeding, trophic feeding, or delayed parenteral feeding may be equivalent or perhaps superior to currently recommended approaches [29,30,31,32].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, although such recommendations appear reasonable from a nitrogen-balance point of view, especially given the loss of amino acids during CRRT [21,22,23,24,25,26,27], the only randomized controlled trial focusing on clinical outcomes was conducted in 1973 [28] and has little relevance to modern practice. Moreover, recent investigations have suggested that permissive underfeeding, trophic feeding, or delayed parenteral feeding may be equivalent or perhaps superior to currently recommended approaches [29,30,31,32].…”
Section: Discussionmentioning
confidence: 99%
“…Table 5 summarises their results [2,3,6,13,14,15,16,17,18,19]. Blood AA levels were mostly higher than or normal compared to reference range or control, with protein intake >2 g/kg/day [2,3,15], while levels were lower when intake was less [14,17].…”
Section: Discussionmentioning
confidence: 99%
“…Sixth, HVHF may be responsible for an important loss of small beneficial molecules including nutrients, amino-acids, vitamins, trace elements, and antimicrobials in the ultrafiltrate. 85,86 Thus, nutritive supplementation (e.g., glutamine) and adaptation of drug prescriptions must be taken into account. 87 Antibiotics levels in particular should be checked whenever possible.…”
Section: Clinical Use Of Hvhfmentioning
confidence: 99%