“…Proline betaine (Pro-B), also known as stachydrine, is a plant osmo-protective compound found in high concentrations in citrus fruits and juices that have emerged as a promising biomarker of citrus intake, given its high abundance in, and relatively high specificity to, these foods [ 37 , 38 , 39 , 40 ]. A number of exploratory studies have identified Pro-B as a known or potential biomarker of consumption of citrus fruit/juice [ 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ], fruit [ 8 , 39 , 49 , 50 ], and/or certain healthy dietary patterns [ 8 , 49 , 51 , 52 , 53 , 54 ].…”