Amino Acids – Technical Production and Use

The McbR repressor modulated by the effector substanceS‐adenosylhomocysteine controls directly the transcription of a regulon involved in sulphur metabolism ofCorynebacterium glutamicumATCC 13032

“…Corynebacterium glutamicum , a Gram‐positive soil bacterium, is widely used in the industrial production of various amino acids, such as l ‐glutamate and l ‐lysine (Hermann, 2003). Unlike most other amino acids, methionine is currently not produced by fermentation but is rather synthesized by a chemical process yielding the racemic d , l ‐methionine that is mainly used as feed additive in animal husbandry (Leuchtenberger et al ., 1996). To enable the future application of C. glutamicum strains in biotechnological production of l ‐methionine, the biosynthetic pathway of this amino acid was the object of intensive research in recent years (Rossol and Pühler, 1992; Park et al ., 1998; Hwang et al ., 1999; 2002; Kim et al ., 2001; Rückert et al ., 2003).…”

Cloning, sequence analysis, expression and inactivation of the Corynebacterium glutamicum pta-ack operon encoding phosphotransacetylase and acetate kinase

“…Corynebacterium glutamicum and its subspecies are widely used for large-scale amino acid production (Leuchtenberger, 1996). This organism grows aerobically on glucose and on acetate as the sole carbon sources and both can also serve as substrates for the production of glutamate, lysine and threonine (reviewed by Kinoshita & Tanaka, 1972).…”

A proteomic study of Corynebacterium glutamicumAAA+ protease FtsH

“…Corynebacterium glutamicum , is a Gram-positive soil bacterium, which is used for the industrial production of different amino acids, mainly L-glutamate and L-lysine, and of nucleotides [1,2]. As a member of the Corynebacterinae, C. glutamicum is closely related to other mycolic acid-containing bacteria, e. g .…”