Amino‐rich Plasma Polymer Films Prepared by RF Magnetron Sputtering

Hanuš, Jan; Ceccone, Giacomo; Rossi, François

doi:10.1002/ppap.201100137

Cited by 8 publications

(6 citation statements)

References 23 publications

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“…Surface plasma modification is an excellent approach to modify the chemical structure 26 and produce the targeted nitrogen functionality 27 28 29 . It has been demonstrated that a nitrogen plasma-modified surface can serve as a powerful artificial microenvironment to regulate osteogenic differentiation of osteoblasts 30 31 32 .…”

Section: Resultsmentioning

confidence: 99%

“…Tertiary amines are produced selectively on the PE in spite of the existence of N-C = O groups due to oxidation. It can be inferred that on the pyrolytic carbon structure, other nitrogen functionalities (for example, -NH 2 ) can be generated by increasing the hydrogen amount in the implanted ions 27 . In addition, most of the C = C bonds remain on PArN implying that the π-conjugated structures are abundant on the PArN surface.…”

Section: Resultsmentioning

confidence: 99%

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Upregulation of BMSCs Osteogenesis by Positively-Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway

Zhang

Liu

Shi

et al. 2015

Sci Rep

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Positively-charged surfaces on implants have a similar potential to upregulate osteogenesis of bone marrow-derived mesenchymal stem cells (BMSCs) as electromagnetic therapy approved for bone regeneration. Generally, their osteogenesis functions are generally considered to stem from the charge-induced adhesion of extracellular matrix (ECM) proteins without exploring the underlying surface charge/cell signaling molecule pathways. Herein, a positively-charged surface with controllable tertiary amines is produced on a polymer implant by plasma surface modification. In addition to inhibiting the TNF-α expression, the positively-charged surface with tertiary amines exhibits excellent cytocompatibility as well as remarkably upregulated osteogenesis-related gene/protein expressions and calcification of the contacted BMSCs. Stimulated by the charged surface, these BMSCs display high iNOS expressions among the three NOS isoforms. Meanwhile, downregulation of the iNOS by L-Can or siRNA inhibit osteogenic differentiation in the BMSCs. These findings suggest that a positively-charged surface with tertiary amines induces osteogenesis of BMSCs via the surface charge/iNOS signaling pathway in addition to elevated ECM protein adhesion. Therefore, creating a positively-charged surface with tertiary amines is a promising approach to promote osseointegration with bone tissues.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Upregulation of BMSCs Osteogenesis by Positively-Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway

Zhang

Liu

Shi

et al. 2015

Sci Rep

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“…The functionalized NCD samples were placed on top of the glass bead layer to avoid direct contact between the sample surface and TFBA liquid. The plastic container was then sealed and placed into an oven at 45° C for 2 h. After the derivatization, the fluorine concentration was determined by XPS and the primary amine [NH 2 ] concentration was calculated as it is described in:

[N {normalH}_{2}] = [\frac{F / 3}{C - (8 F / 3)}] \times 100 %

where F and C are the fluorine and carbon concentrations, respectively, after the reaction with TFBA. The term F/3 then indicates the amount of primary amines, the term 8F/3 corresponds to the amount of carbon atoms added by TFBA molecules themselves and the term C − 8F/3 is the original carbon concentration on the surface …”

Section: Methodsmentioning

confidence: 99%

Amination of NCD Films for Possible Application in Biosensing

Artemenko

Kozak

Biederman

et al. 2014

Plasma Process. Polym.

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Nanocrystalline diamond (NCD) films may be used in biosensing after modification of their surfaces with active functional groups. Here, surface functionalization of O-and H-NCD films with amine groups was made by 2 plasma-based processes: a) RF plasma treatment in ammonia, b) the deposition of thin amine-containing plasma polymer via RF magnetron sputtering of nylon target in Ar/N 2 mixture. Amination of the NCD films by plasma treatment in NH 3 caused an attachment of 1% of primary amines but destroyed the surface conductivity of H-NCD films. The 5% concentration of -NH 2 was detected on the NCD covered with the plasma polymer. Moreover, the surface conductivity of H-NCD films reached 10 À7 S.

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“…The present work provides the first chemical analysis of tholins thin films along their depth profile, using XPS (X-ray Photoemission Spectroscopy) -3 -and SIMS (Secondary Ion Mass Spectrometry) analysis. Those two techniques are commonly used for organic films analysis in general, [22][23][24][25] and are well adapted for nitrogen containing films in particular [26][27][28]. Moreover two kinds of substrates are used, made of CaF 2 and SiO 2 , to analyze the sensitivity of the solid deposition to the nature of the substrate.…”

Section: Introductionmentioning

confidence: 99%

Laboratory analogues simulating Titan's atmospheric aerosols: Compared chemical compositions of grains and thin films

Carrasco

Jomard

Vigneron

et al. 2016

Planetary and Space Science

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Two sorts of solid organic samples can be produced in laboratory experiments simulating Titan's atmospheric reactivity: grains in the volume and thin films on the reactor walls. We expect that grains are more representative of Titan's atmospheric aerosols, but films are used to provide optical indices for radiative models of Titan's atmosphere.The aim of the present study is to address if these two sorts of analogues are chemically equivalent or not, when produced in the same N 2 -CH 4 plasma discharge. The chemical compositions of both these materials are measured by using elemental analysis, XPS analysis and Secondary Ion Mass Spectrometry. The main parameter probed is the CH 4 /N 2 ratio to explore various possible chemical regimes. We find that films are homogeneous but significantly less rich in nitrogen and hydrogen than grains produced in the same experimental conditions. This surprising difference in their chemical compositions could be explained by the efficient etching occurring on the films, which stay in the discharge during the whole plasma duration, whereas the grains are ejected after a few minutes. The higher nitrogen content in the grains possibly involves a higher optical absorption than the one measured on

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Amino‐rich Plasma Polymer Films Prepared by RF Magnetron Sputtering

Cited by 8 publications

References 23 publications

Upregulation of BMSCs Osteogenesis by Positively-Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway

Upregulation of BMSCs Osteogenesis by Positively-Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway

Amination of NCD Films for Possible Application in Biosensing

Laboratory analogues simulating Titan's atmospheric aerosols: Compared chemical compositions of grains and thin films

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