Aminocarbonylation of 1,1′-diiodoferrocene, two-step synthesis of heterodisubstituted ferrocene derivatives via homogeneous catalytic carbonylation/coupling reactions

Synthesis of 1,1′-ferrocene bis(carboxypyrazole) compounds and displacement of the pyrazole ligands

“…Attempts to bind the new ferrocene compounds as bidentate ligands to a Mo(CO) 4 fragment did not produce the desired Mo(CO) 4 (N-N) complex. Instead, after a short reflux in CH 2 Cl 2 , both pyrazole rings were displaced and replaced with piperidine ligands from the molybdenum carbonyl reagent yielding the known compound, Fe(C 5 H 4 CONHC 5 H 10 ) 2 [17,18]. We attempted to determine whether the pyrazoles replaced the piperidines on the molybdenum metal center.…”

Synthesis and Electrochemical Properties of N-(Ferrocenylmethyl)Aminobenzonitrile and N-(Ferrocenylmethyl)Nitroaniline Derivatives

“…In recent years, the design of new ferrocene derivatives has been of considerable interest, because of their utility in organic synthesis [1], catalysis [2], materials science [3,5], asymmetric synthesis [6], medicinal chemistry [7][8] and electrochemistry [9][10][11][12]. Our interests in ferrocene derivatives containing (methylamino)benzonitrile and N-methylnitroaniline groups arises from the fact that similar compounds such as N-(ferrocenylmethyl)benzene-carboxamide derivatives possess broad range of biological activities [13].…”

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

“…[30][31][32][33][34][35][36][37][38] Ferrocene is an organometallic molecule that is a gold standard for electrochemistry, which makes it an excellent choice for integration into electrochemical biosensors. Ferrocene-based redox active species have already garnered considerable attention due to their small size, good stability, convenient synthetic access, easy chemical modification, relative lipophilicity, and ease of redox tuning.…”

“…Ferrocene-based redox active species have already garnered considerable attention due to their small size, good stability, convenient synthetic access, easy chemical modification, relative lipophilicity, and ease of redox tuning. 3,[30][31][32][33][34][35][36][37][38][39][40][41][42] Small molecules based on the ferrocene core have been used extensively as detectors of metal ions and small molecules. [32][33][34][35][36][37][38]43 Systems targeting larger species such as biomolecules have utilized the attachment of large antibodies or immunoglobulins to ferrocene derivatives that have been embedded onto an electrochemical surface.…”