Amitriptyline Intoxication in Children

Abstract

Background: Amitriptyline ingestion is an important cause of poisoning morbidity and mortality in Turkey and other countries. In contrast to adults, data concerning amitriptyline intoxication in children are limited. The purpose of this study was to investigate amitriptyline intoxication findings in the pediatric population, based on age groups and reported dosages.

Cardiovascular Manifestations After Amitriptyline Poisoning in the Last Five Years

“…These studies were published in the years 2019-2022, by authorsButt et al (2019),Jansen et al (2019),Kamasak et al (2021), andRyan et al (2022) Butt et al (2019). state in their document (case report) that the use of amitriptyline can cause toxicity when the combined serum level of amitriptyline and its active metabolite (nortriptyline) is greater than 300 ng/mL (normal, 80-200 ng/mL )(Butt et al, 2019).One of these nine studies is an experimental study that was published by the corresponding author,Jansen et al (2019), from Denmark.…”