2023
DOI: 10.1021/acs.chemrestox.3c00368
|View full text |Cite
|
Sign up to set email alerts
|

Ammonia Toxicity and Associated Protein Oxidation: A Single-Cell Surface Enhanced Raman Spectroscopy Study

Davide Redolfi-Bristol,
Alessandro Mangiameli,
Kenta Yamamoto
et al.

Abstract: Ammonia (NH 3 ) is a commonly used industrial chemical to which exposure at high concentrations can result in severe skin damage. Moreover, high levels of ammonia in the human body can lead to hyperammonemia conditions and enhanced cancer metabolism. In this work, the toxicity mechanism of NH 3 has been studied against human dermal fibroblast (HDF) cells using surface-enhanced Raman spectroscopy (SERS). For this purpose, gold nanoparticles of size 50 nm have been prepared and used as probes for Raman signal en… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 65 publications
0
1
0
Order By: Relevance
“…As known, ammonia is utilized extensively in many industries. Detection of ammonia is especially important as it could lead to toxic build-up in tissues and blood [ 35 ]. The toxicity is related to the concentration in the environment and the exposure time.…”
Section: Introductionmentioning
confidence: 99%
“…As known, ammonia is utilized extensively in many industries. Detection of ammonia is especially important as it could lead to toxic build-up in tissues and blood [ 35 ]. The toxicity is related to the concentration in the environment and the exposure time.…”
Section: Introductionmentioning
confidence: 99%