Ammonium acetate as a novel buffer for highly selective robust urinary HPLC-ICP-MS arsenic speciation methodology

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

“…The mobile phase is composed of acetic acid and methanol or acetonitrile ( Madani-Tonekaboni et al., 2015 ). Alternatively, this mycotoxin analysis employs ammonium acetate ( Panwalkar et al., 2017 ; Rodriguez et al., 2021 ). The target molecule is highly polar, which results in low sensitivity for the LC-MS analysis.…”

Rapid automated total arsenic and arsenic speciation by inductively coupled plasma mass spectrometry

“…Some organic forms (dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA)) are less toxic due to a lower bioavailability, while other organic forms of arsenic such as arsenobetaine (AsB), arsenocholine (AsC), and trimethylarsine oxide (TMAO) are considered non-toxic. 7–11…”

“…The most common methodology for measuring total arsenic is performed using an inductively coupled plasma-mass spectrometer (ICP-MS), whereas determining the arsenic species is typically done by chromatographic separation prior to introduction to the ICP-MS. A large amount of work has been dedicated to this topic in recent decades, however the resulting methods are generally lengthy, offer only a sub-set of the arsenic species, and/or have high operational costs. 2,11,14–26 Wegwerth et al presented the fastest method (2 minutes) for arsenic speciation to date but it did not include TMAO. 25 Ciardullo et al presented a method for seven arsenic species (AsB, AsC, DMA, MMA, TMAO, As( iii ), and As( v )), however 25 minutes were needed to complete the separation.…”