Ammonium based ionic liquids act as compatible solvents for glycine peptides

Volumetric, ultrasonic and UV absorption studies on interactions of antibiotic drug chloramphenicol with glycine and its dipeptide in aqueous solutions at T = (288.15–318.15) K

“…A significant study is made by such model compounds because their structures can be transformed easily and the contribution of side chain groups of amino acid/peptide chain could also be a governing factor in deciding the type and magnitude of interactions. Various physicochemical properties of constituent amino acids, peptides and their derivatives in aqueous and mixed aqueous solutions have been utilized by numerous researchers to scrutinize solute-solvent interactions [21][22][23][24][25][26][27][28][29][30][31]. A vital role is played by drug-protein interactions in all the metabolic pathways or biological processes occurring inside the body.…”

Salting-out behaviour of 1-butyl-3-methylimidazolium bromide, [C4mim][Br], ionic liquid on aqueous l-serine solutions at T=298.15K

“…In 1960-1970, Nozaki and Tanford [40][41][42] noted that the activity coefficient term is a selfinteraction coefficient term and found that the ratio of the activity coefficient term makes only a small contribution to ∆transfer G′ . Therefore, many researchers [10,[15][16][17][18][40][41][42][43][44] have ignored the activity coefficient term on the right-hand side of Eq. 14 for determining transfer Gibbs energy of various solutions.…”

“…For this purpose, water activity for the ternary system {L-serine + [C 4 mim][Br] + H 2 O} was measured using the improved isopiestic method at T = 298.15 K. Furthermore, to have a better insight about the interactions between IL and amino acid solutions, we also measured the solubility of L-serine in aqueous [C 4 mim][Br] solutions at 298.15 K using the gravimetric method. With regard to the solubility of biomolecules, peptides and amino acids in aqueous ILs solutions, only very few reports have been given recently [14][15][16][17][18].…”

Structural Heterogeneities in Solutions of Triethylamine Nitrate Ionic Liquid: 1H NMR and LC Model Study

“…On the one hand, they have general characteristics like other ILs such as low volatility, wide liquid range, good solubility with other solvents and are function adjustable according to different combinations of cations and anions. On the other hand, they also have many special properties, including low cost, high electrical conductivity, and ease of preparation through direct neutralization between corresponding acid and base, which can endow them excellent performance in many fields such as alkylation reactions [1], absorption of SO 2 [2] and CO 2 [3], extraction of soluble dyes [4], stability of proteins [5,6], dissolution of cellulose [7], electrochemistry [8] and wastewater treatments [9]. Obviously, knowledge of interactions between ammonium based ILs and molecular solvents is essential for their applications in chemical and industrial processes.…”